Anatomy Mnemonics Flashcards
What does the mnemonic ‘BOATS’ represent in collagen types?
Bone (Type I - Osteogenesis Imperfecta), Ocular (Type II - Stickler syndrome), Aorta (Type III - Vascular Ehlers-Danlos), Tubules (Type IV - Alport syndrome), Skin (Type VII - Epidermolysis bullosa)
Represents major collagen types and associated diseases.
What are the key components of collagen synthesis represented by ‘G-PP’?
Gly-X-Y repeats, Proline hydroxylation (needs Vitamin C), Procollagen → Tropocollagen
Highlights important steps in the synthesis of collagen.
What does ‘SLiM-DoC’ stand for regarding cartilage zones?
Superficial (Lubricin), Middle (aggrecan Matrix), Deep (Collagen anchors), Calcified (attaches to bone)
Describes the layers of articular cartilage.
What does the mnemonic ‘WITCH’ refer to in bone regulation pathways?
Wnt binds Inhibitors (Dkk-1/Sclerostin), TCF/LEF activation, Catenin stabilization, High bone mass when blocked
Summarizes the Wnt signaling pathway in bone regulation.
What does ‘ROCK’ signify in the context of the RANKL pathway?
RANKL → Osteoclast On, Clotting (OPG Kills activation)
Details the RANKL pathway’s role in osteoclast activation.
What are the normal findings in synovial fluid summarized by ‘VISC’?
Viscous (string sign 2-5 cm), Inflammatory cells <200/mm³, Serum glucose (within 20 mg/dL), Colorless/clear
Indicates the characteristics of normal synovial fluid.
What does ‘SO-FG’ represent regarding muscle fiber types?
Slow (Type 1 - Oxidative), Fast (Type 2b - Glycolytic), Glycogen-rich (Type 2b)
Classifies different types of muscle fibers based on their physiology.
What is summarized by the mnemonic ‘SCURVY’ regarding collagen defects?
Subperiosteal hemorrhage, Corkscrew hairs, Unstable collagen, Rough skin, Vitamin C deficiency, Yellow sclerae
Lists clinical features of collagen defects associated with Vitamin C deficiency.
What does ‘MARFAN’ describe in relation to fibrillin-1 defects?
Mitral valve prolapse, Aortic dissection, Rarachnodactyly, Flat feet, Acanthosis nigricans (sometimes), Nearsightedness
Identifies clinical manifestations of Marfan syndrome.
Fill in the blank: The structure of collagen can be visualized as a _______ with ‘GXY’ written on each rung.
triple rope ladder
Helps to remember the helical structure of collagen.
Fill in the blank: The process of bone remodeling can be imagined as a _______ site.
construction
A visual analogy to understand the roles of different pathways in bone remodeling.
Fill in the blank: Cartilage zones can be visualized as a _______ with layers representing different zones.
layer cake
A mnemonic to help remember the structural organization of cartilage.
Wie merkt man sich die wichtigsten Kollagen-Typen?
F.A.S.T.
- Fibrillär (I: Knochen, II: Knorpel, III: Gefäße)
- Anker (IV: Basalmembran, VII: Hautankerfibrillen)
- Spezial (X: Wachstumsplatte)
- Transparent (IX/XII: Knorpel-Crosslinks)
Visualisierung: “FAST wie Kollagenfasern wachsen!”
Die 4 Knorpelzonen?
STeR C
- Superfiziell (Tangentialfasern)
- Transitional
- Radial (tiefe Zone)
- Calcified (verkalkt)
“STeR-C wie Sternchen im Knorpel!”
Eigenschaften normaler Synovia?
4x H
- Hell (farblos)
- Hochviskös (Hyaluronat)
- Handvoll Zellen (<200/µl)
- Halb so viel Protein (1.3-1.7 g/dL)
“H wie Heilige Synovia!”
Wie merkt man sich RANKL/OPG?
ROK
- RANKL = Osteoklasten-Kickstarter
- OPG = Osteoklasten-Pause
“ROK wie Rockmusik (laut=RANKL, leise=OPG)!”
Was hemmt den Wnt-Signalweg?
SDS
- Sclerostin
- Dickkopf-1
- SFRPs (secreted frizzled-related proteins)
“SDS wie Waschmittel (wäscht Wnt weg)!”
Die 3 Muskelfasertypen?
SO FG
- SO (Typ I: Slow Oxidative)
- FG (Typ 2a: Fast Glycolytic)
- FG (Typ 2b: Fastest Glycolytic)
“SO FG wie ‘So fettig’ (Fett=Typ I, Zucker=Typ 2)!”
Haupt-Glykosaminoglykane?
HAS KCD
- Hyaluronat
- Aggrecan (Chondroitinsulfat)
- Syndecan
- Keratan
- Chondroitin
- Dermatan
“HAS KCD wie ‘Hat’s gekostet?’ (teure Matrix)!”
Schritte der Kollagenbildung?
HOT GPS
- Hydroxylierung (Pro/Lys)
- Oligosaccharid-Anhang
- Triplehelix (Prokollagen)
- Golgi-Verpackung
- Peptidasen (Tropokollagen)
- Stabilisierung (Quervernetzung)
“HOT GPS wie Navi für Kollagenproduktion!”
Klassifikation von Gelenken?
SAD
- Synarthrose (unbeweglich)
- Amphiarthrose (leicht beweglich)
- Diarthrose (frei beweglich)
“SAD wie Traurigkeit über Gelenksteife!”
Wie aktiviert Wnt Osteoblasten?
WOW
- Wnt bindet LRP5/6
- Ohne GSK-3β (β-Catenin akkumuliert)
- Wachstum (Genexpression)
“WOW-Effekt der Knochenbildung!”
Was bedeutet ‘Vitamin C = Collagen-Crew’?
Skorbut → keine Hydroxylierung
Vitamin C ist essentiell für die Kollagenbildung.
Was bedeutet ‘Marfan = Fibrillin-1 Fails’?
Fibrillin-1-Mutation → Aneurysmen
Marfan-Syndrom ist mit Fibrillin-1 assoziiert.
