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Flashcards in Blood Banking Deck (21):
1

Blood type A

you have A antigen on the surface of the RBC and B antibodies in your blood plasma

2

which blood type is the universal donor?

O

3

which blood type is the universal recipient?

AB

4

what type of blood cells are transferred in a transfusion?

RBC

5

how does a hypersensitivity reaction present?

mild fever
anaphylaxis
severe hemolysis
chills
rash
back pain
bloody urine
fainting

6

what is cross matching?

testing performed prior to a transfusion to determine if blood types are compatible for organ transplants

7

agglutination reaction

clumping of the red blood cells because of mismatch transfusion

8

Rh factor

Rh antigen on the RBC indicated by + or - on blood type

9

hydrops fetalis

when RBC of the fetus are destroyed by the Rh antibody of the mother

10

who is Landsteiner?

he discovered the Rh factor in 1940 and he also discovered ABO blood types

11

what is the Direct Coombs test? (DAT or direct antiglobulni test)

used to identify if there is lysis of the RBC
used to detect hemolytic transfusion reaction
-identifies antibodies that are attached to the RBC

12

how is the DAT test done?

Coombs reagent involved and if there is agglutination you will be able to visual it

13

indirect Coombs test or IAT

used in prenatal testing of pregnant women and in testing blood prior to blood transfusion

14

how is the Coombs test done?

serum is extracted then incubated with RBCs of known antigenicity

15

why do we give blood transfusions?

increase oxygen-carrying capacity
increase total blood volume

16

when should you give a blood transfusion? (oxygen carrying)

unlikely for hemoglobin >10 g/dL
in between 10 and 6 if pt has major disease such as emphysema or ischemic heart disease
definite for hemoglobin <6 g/dL

17

when should you give a blood transfusion?
(volume)

blood loss of more than 20% (100 ml)

18

what is TRALI?

transfusion related acute lung injury
-rare but usually seen within the first 6 hours

19

what is the presentation of TRALI?

acute onset of dyspnea
severe hypoxemia
hypotension
fever

20

delayed hemolytic transfusion reaction

due to hemolysis of previously unknown antibody

21

what labs would be indicated in suspected DHTR?

look for falling Hgb
newly positive antibody screen
spherocytes on smear

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