Flashcards in Lipoproteins and Cardiac Enzymes Deck (49)
where is cholesterol metabolized?
what transports cholesterol in the blood?
why can cholesterol be a problem?
associated with atherosclerotic disease
what is the main function of cholesterol?
production of steroids, sex hormones, bile acids and cell membrane
what can also cause low levels of cholesterol?
liver disease and malnutrition
what coronary predictor is used to identify CAD risk from cholesterol?
what are the 5 major lipoproteins? present on the standard lipid panal
what do chylomicrons do?
carry fat from the GI tract to liver, skeletal muscle and adipose tissue
-they are very large particles
what do VLDLs do?
carries endogenous (self-made) triglycerides from liver to adipose tissue
(when it is high it means that there is a lot of endogenous cholesterol)
what do IDLs do?
carries cholesterol esters and triglycerides
-usually not detectable
what do LDLs do?
carries cholesterol esters from liver to cells of the body
what do HDLs do?
collects cholesterol from tissues and vacular endothelium and returns it to the liver
-has a protective effect against heart disease
what is reverse transport?
when HDL takes cholesterol in the vasculature and returns it to the liver
how can we increase HDL?
what do triglycerides do?
acts as a storage source for energy, when they are high they are deposited in fatty tissues
how are triglycerides transported?
VLDL and LDL
what purposed does the lipid profile serve?
assess CAD risk
assess vascular dz risk
what is on a lipid profile?
what are the normal adult TCC values?
what is the critical value of TG?
what are the normal HDL values?
what are the normal LDL values?
what TG value would cause an inaccurate LDL?
what is the normal range of VLDL?
how do you calculate LDL?
what instructions are important for lipoprotein study?
12-14 hr fast
low fat meal prior to fast
what can interfere with cholesterol levels?
pregnancy increases levels
recumbent positions decrease levels
postmenopausal states cause increased levels
what can impact HDL levels?
post MI decreases
liver dz and malnutrition decreases
main drugs that alter lipoprotien