Flashcards in Renal Studies Deck (18)
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1
glomerular filtration rate
ability of the kidneys to clear out waste products
2
what is a normal GFR per day?
150-250 L/24 hrs
3
why do we measure kidney function with creatinine?
it is always being sloughed off from muscles
4
low level of creatinine in urine means
low kidney function
5
what are the three ways to estimate GFR?
1. Cockcroft-Gault formula
2. MDRD (modification of diet in renal dz)-best estimate
3. 24 hr urine
6
what does MDRD help to differentiate?
race and gender and age
-AA progress slower
-males have higher protein
7
what does Cockcroft-Gault help to differentiate?
male/female and age
8
how is ESRD defined?
on dialysis or GFR of <15%
9
what is the formula for Cockcroft-Gault?
[(140-age) x wt (kg)] / (Plasma Cr x 72)
10
what do you multiple Cockcroft-Gault times to adjust for female?
0.85
11
what is a restriction of Cockcroft-Gault?
overestimates GFR in obese and edemous patients
12
what has to happen when pt turns in a 24 hour urine specimen
get serum Cr!!!!!!!!!!!
13
what is the Cr clearance equation?
(UCr x Uv) / (SCr x time (1440 minutes))
14
what is an acceptable proteinuria value?
< 150mg/24hrs
15
what is acceptable proteinuria value for DM pts?
<30mg/ 24hr
16
what is the nephrotic range of proteinuria?
>3.5 g / 24 hrs
17
which spot test will you order with high risk pt with negative dipstick?
albumin-creatinine ratio
normal is < 30
18