Flashcards in Innate Immunity Deck (39):
which areas of the body do not have lymphatic vessels?
which cells are most abundant in the lymph nodes?
what is lymph fluid called?
which two mechanisms facilitate movement of chyle?
contraction of skeletal muscle
what are Hassel's corpuscles/
located in the medulla of the thymus
epithelial cells filled with keratohyaline granules
what is the role of nurse cells?
secrete thymic hormones that mature and differentiate T-cells
what is located in the outer cortex of lymph nodes?
what is located in the medulla of lymph nodes?
B cells and macrophages
what is located in the inner cortex of lymph nodes?
what CT fibers support lymph nodes?
what is found in the white pulp of the spleen?
B and T cells surrounding branches of the splenic artery
Immune system component
what is found in the red pulp of the spleen?
blood-filled venous sinuses
removes worn out RBC and WBC
which chemical on the skin is resistant to bacterial enzymes?
which features do mucosal membranes use to fight bacteria?
sebum contains chemical toxin
stomach digests proteins
tenacious to trap organisms
cilia to move them out
which cells produce interferon?
virally-infected lymphocytes and macrophages
what does interferon do?
induces synthesis of antiviral proteins
which cells produce alpha interferon?
which cells produce beta interferon?
which cells produce gamma interferon?
what 3 things does the complement system do?
1. promotes phagocytosis
2. causes inflammation
3. causes cytolysis
how does iron binding contribute to innate immunity?
traps iron, which bacteria needs to replicate
what do AMP's do?
work in a variety of ways against many organisms
which cell has the selectin?
blood vessel endothelial cell
which cell has the integrin?
what two components does opsonization need?
1. complement (innate)
2. IgG (adaptive)
what do defensins do?
pierce a whole in the bacterium cell wall
which cells can kill cancer and virally infected cells?
what important areas contain NK cells?
how do NK cells know which cells to kill?
contains a stress-induced glycoprotein on cell surface
lacks MHC 1 protein
what two proteins do NK cells use to kill cells?
what do granzymes do?
penetrate bacterial cells and destroy their insides
what are 2 main functions of the inflammatory response?
2. increased capillary permeability
which 3 things cause pain from injury?
which coagulation factor is responsible for the kinin cascade?
which prostaglandin is responsible for platelet aggregation?
which prostaglandin is responsible for protecting tissue surrounding the clot?
what are the 3 results of the complement system?
2. MAC attack
3. causes inflammation
what stimulates zinc and iron binding?