Flashcards in Psychotropics Deck (13)
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1
where should MOAIs be managed?
not at the primary care level
psychiatrist
2
which SSRIs are structurally similar?
lexapro and celexa
3
what are other indications of SSRI?
OCD, panic d/o, GAD, PMDD, SAD, eating disorders
4
which SSRI has the longest half life?
prozac 4-6 days
5
what is the peak action of SSRIs?
3-8 hrs
6
where are SSRIs metabolized?
CYP450 enzyme in the liver
7
which SSRI has most liver metabolic problems?
luvox
8
what is the MOA of SSRI?
inhibit re-uptake of 5HT making more serotonin available
little effect on dopamin and norepi
9
which SSRI has significant anticholinergic activity at higher doses?
paxil
10
how does SSRI withdrawal present?
flu like
N. fatigue, myalgia, vertigo
11
what are SE of SSRI?
h/a, dizziness, N, D, insomnia, sexual dysfunction (everything goes away with long term use except for sexual dysfunction)
12
what are drug interactions that can cause serotonin excess?
SSRI + MAOI OR Triptan OR lithium
13
