Psychotropics Flashcards Preview

Medicine > Psychotropics > Flashcards

Flashcards in Psychotropics Deck (13):
1

where should MOAIs be managed?

not at the primary care level
psychiatrist

2

which SSRIs are structurally similar?

lexapro and celexa

3

what are other indications of SSRI?

OCD, panic d/o, GAD, PMDD, SAD, eating disorders

4

which SSRI has the longest half life?

prozac 4-6 days

5

what is the peak action of SSRIs?

3-8 hrs

6

where are SSRIs metabolized?

CYP450 enzyme in the liver

7

which SSRI has most liver metabolic problems?

luvox

8

what is the MOA of SSRI?

inhibit re-uptake of 5HT making more serotonin available
little effect on dopamin and norepi

9

which SSRI has significant anticholinergic activity at higher doses?

paxil

10

how does SSRI withdrawal present?

flu like
N. fatigue, myalgia, vertigo

11

what are SE of SSRI?

h/a, dizziness, N, D, insomnia, sexual dysfunction (everything goes away with long term use except for sexual dysfunction)

12

what are drug interactions that can cause serotonin excess?

SSRI + MAOI OR Triptan OR lithium

13

what is hallmark of serotonin syndrome?

**mental status change
**autonomic hyperactivity
**neuomuscular abn
D, restlessness, agitation, hyperreflexives, myoclonus, seizures, hyperthermia, AMS, death

Decks in Medicine Class (146):