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Flashcards in blood transfusions Deck (24):
1

3 parts in blood

1. plasma
2. buffy coat
3. RBCs

2

what is alternative to RBCs for anemia

Fe

3

what's in a unit of RBC

160ml RBC
1-20 plasma
100ml anticoag

4

how much does 1 unit raise Hb

10g/L

5

3 levels of Hb and what to give

>90 - no
70-90 - depends on PT factors

6

what is recommendation of symptomatic CAD

>90 - no
70-90 - depends on PT factors - even in CAD and elderly, closer to 80

7

how to transfuse RBCs

1 unit at a time over 2 hours and not more than 4 hours
- consider slower with furosemide if imparied cardiac funct
- assess outcome befoer more

8

2 times to be cautious about platelet transfusions

1. trombotic thromobocytopenic dis.
- TTP
- HIT
- ALPA
2. immune thrombocytopenia
- prednisone more effective

9

manifestations of thrombopenia

1. proimary hemo stasis issues
2. bleeds

10

what in dose of platlets

1 boffy coat of plts from 4 donors
= 250-300 ml

11

how much does one unit of plts raise

count by 15-20

12

when to tranfuse platelets (4 levels)

under 10 - prevent spont. bleeds

13

how to tansfuse plts

1 dose over 1-2 hours max 4

14

what happens in low clotting factors

bleeds - high IRN
- require levels at 30-50%

15

whats in a unit of flozen plasma

250ml
all necc. clotting factors
1/2 life 6-8 hours

16

how much for a dose

brings up factors by 20%

17

2 times to give plasma

1. major bleed or procedure and INR>1.5
2. microvasc bleeds and cannot wait for labs

18

3 practical tips for frozen plasma

must be thawed
- must be ABO compatible
- universal is AB plasma

19

what are prothrombin complex concentrates

Vi K factors - 10,9,7,2, C,S
pooled
for urgent or emergent reversal of warfarin

20

how to give PCC

1000 units over 15 minutes
- need to give vit K for prolonged reversal

21

what are probs. with low fibrinogen

- microvasc bleed
- complicate massive hemmorhage

22

what is in unit of cryoprecipitate

15mls
- fibrinogen and factor 8, 13, VWF

23

what does does (10 units) raise by

0.5g/l

24

2 levels to give cryoprecipitate

fibro

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