Coronary artery disease Flashcards Preview

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Flashcards in Coronary artery disease Deck (13):
1

4 main arteries of heart and what they supply

L coronary - Lat
R cor - Med
LAD - ant
posteior - inferior

2

5 things that happen to endothelial cells in artheriosclerosis

1. up - permiability
2. up - ionlfamation
3. up - leukocyte adhesion
4. down - vasodilation molecules
5. down - antithrombotic mechs

3

5 systemic causes of endothelial dysfunction

1. hypertension
2. diabetes
3. dyslipidemia
4. smoking
5. systemica inflammation

4

1 local cause of endo dysfunction

sheer stress

5

what happens to artery in artheriosclerosis

fatty streaks in the smooth mnucles layer

6

why can you have a big plaque with no symptoms

grows outwardly

7

when during a heart beat does perfusion occur

diastole

8

3 things that influence O2 demand in heart

1. rate
2. wall stress
3. contractility

9

when stenosis become a problem

70-80% range

10

what causes an unstable plaque

thinning of collagen due to inflammation

11

what happens if thin collagen cap ruptures

thrombotic response

12

what can be measured as a measure of MI and when do levels peak

troopnin - 2 days after

13

what is difference between stable and unstable angina

plaque rupture

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