1. otitis media 2. sinusitis 3. pharynigitis 4. pneumonia 5. meningitis

1. diverticoutis 2. intra-abdo abscess 3. cholecyctitis 4. pyelonephritis 5. PID 6. diabetic foot infection

1. cellulitis 2. erysipelas 3. abscess

1. vancomycin 2. trimethoprim-sulfa 3. nitrofuenatoin 4. metronidazole 5. clindamycin

Shreiber ABs Flashcards by Seth Davis

7 bugs in resp. cluster

pneumococcus
H. influenzae
Moraxella catarrhalis
meningococcus
chlamydophylae pneumoniae
mycoplasma pneumonaie
Group A strep

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5 resp. syndromes

otitis media
sinusitis
pharynigitis
pneumonia
meningitis

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3 bugs in intra-abdo cluster

Gr- bacilli
anaerobes
enterococci

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6 abdo syndromes

diverticoutis
intra-abdo abscess
cholecyctitis
pyelonephritis
PID
diabetic foot infection

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2 bugs in skin

Group A strep

2. S. aureus

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3 syndromes in skin

cellulitis
erysipelas
abscess

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what are 3 big AM families

penicillins
cephalosporins
FQs

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4 “pretty big” families

outpatients
1. macrolides
2. tetracyclines
inpatients
1. carbapenems
2. aminoglycosides

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5 individuals

vancomycin
trimethoprim-sulfa
nitrofuenatoin
metronidazole
clindamycin

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bugs for penicillin

strep, pneumococcus, treponium pallidium

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bugs for ampi/amoicillin

amino group

-strep, pneumococcus, treponium pallidium + some Gr-

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what are 2 add-ons for penicillins

clavulanate or tazo - give broader spectrum

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coverage for cloxacillin

same as penicillin, but with S. Aureus

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2 important groups of cephalosporins and names

1st gen - cephalexin and cefazolin

3rd gen - cefixime, ceftriaxone, cefrazidime

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what do 2 generations cover

1st - Gr+

3rd - Gr-

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2 keys FQs and their coverage

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ciprofloxacin - aerobic Gr- rods

2. respiratory FQs (levofloxacin, moxifloxacin) - aerobic Gr- rods, bacteria causing pneumonia, aerobic Gr- cocci

coverage by macrolides

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Gr+ cocci, bacteria causing pneumonia, some Gr- including those causing gon and traveller diarrhea

coverage by tertacyclines

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pneumonia bacteria, chlamydia, broad spectrum including MRSA

coverage by aminoclycocides

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aerobic Gr-

coverage by carbapenems

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everything but MRSA

coverage by trimethoprim-sulfa

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broad spectrum, esp Gr- , MRSA

coverage by nitrofurantoin

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Gr- bacillis, enterococcus (BOTH only for CYSTITIS)

coverage by metronidazole

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anaerobes, C.diff

coverage by clindamycin

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Gr+ cocci (yes MRSA, no enterococci), anaerobes

coverage by vancomycin

aerobic Gr+ cocci

1st and 2nd choice for Strep A

1. penicillin | 2. 1st gen cephalosporin, macrolide, resp. FQ

1st and 2nd choice for Strep pneumoniae

1. penicillin | 2. 2 or 3 gen cephal, macrolide, resp FQ, vanco

1st and 2nd choice for entercoccus

1. amoxicillin | 2. vanco, linolizid

1st and 2nd choice for s. aureus (non-MRSA)

1. cloxacillin | 2. 1st gen. cephalo, vanco

1st and 2nd choice for MRSA

1. blood - vanco, skin- clindamycin

Choices for typical enteric pathos (E.coli, proteus, klebsiella)

1. FQ 2. 3rd gen cephalo 3. amoxicillin-clav

choices for H. influenzae, moraxella

1. amoxicillan 2. cephalo - 3rd gen 3. resp FQ

choices for neisseria meningitidis and gonorrhea

1. 3rd gen cephalo (ceftriaxone) | 2. add azithromycin or doxicylin for gon

drugs for chlamydia trachomatis and mycoplasma pneumoniae

1. azithromycin | 2. doxicycline

drugs for bacteroides and other oral and gut anaerobes

metronidazole

drugs for C.diff

metronidazole

8 issues to think about when choosing the meds

1. local resistance patterns 2. recent AB use 3. co-morbidities that may alter 4. if the patient is very sick 5. cost 6. safety issues 7. tissue penetration 8. cidal vs .static 9. evidence from randomized trials

what to do when culture is returned

narrow the spectrum

go through the samples

now

Shreiber ABs Flashcards

(39 cards)