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Flashcards in Shreiber ABs Deck (39):
1

7 bugs in resp. cluster

1. pneumococcus
2. H. influenzae
3. Moraxella catarrhalis
4. meningococcus
5. chlamydophylae pneumoniae
6. mycoplasma pneumonaie
7. Group A strep

2

5 resp. syndromes

1. otitis media
2. sinusitis
3. pharynigitis
4. pneumonia
5. meningitis

3

3 bugs in intra-abdo cluster

1. Gr- bacilli
2. anaerobes
3. enterococci

4

6 abdo syndromes

1. diverticoutis
2. intra-abdo abscess
3. cholecyctitis
4. pyelonephritis
5. PID
6. diabetic foot infection

5

2 bugs in skin

1. Group A strep
2. S. aureus

6

3 syndromes in skin

1. cellulitis
2. erysipelas
3. abscess

7

what are 3 big AM families

1. penicillins
2. cephalosporins
3. FQs

8

4 "pretty big" families

outpatients
1. macrolides
2. tetracyclines
inpatients
1. carbapenems
2. aminoglycosides

9

5 individuals

1. vancomycin
2. trimethoprim-sulfa
3. nitrofuenatoin
4. metronidazole
5. clindamycin

10

bugs for penicillin

strep, pneumococcus, treponium pallidium

11

bugs for ampi/amoicillin

amino group
-strep, pneumococcus, treponium pallidium + some Gr-

12

what are 2 add-ons for penicillins

clavulanate or tazo - give broader spectrum

13

coverage for cloxacillin

same as penicillin, but with S. Aureus

14

2 important groups of cephalosporins and names

1st gen - cephalexin and cefazolin
3rd gen - cefixime, ceftriaxone, cefrazidime

15

what do 2 generations cover

1st - Gr+
3rd - Gr-

16

2 keys FQs and their coverage

1. ciprofloxacin - aerobic Gr- rods
2. respiratory FQs (levofloxacin, moxifloxacin) - aerobic Gr- rods, bacteria causing pneumonia, aerobic Gr- cocci

17

coverage by macrolides

Gr+ cocci, bacteria causing pneumonia, some Gr- including those causing gon and traveller diarrhea

18

coverage by tertacyclines

pneumonia bacteria, chlamydia, broad spectrum including MRSA

19

coverage by aminoclycocides

aerobic Gr-

20

coverage by carbapenems

everything but MRSA

21

coverage by trimethoprim-sulfa

broad spectrum, esp Gr- , MRSA

22

coverage by nitrofurantoin

Gr- bacillis, enterococcus (BOTH only for CYSTITIS)

23

coverage by metronidazole

anaerobes, C.diff

24

coverage by clindamycin

Gr+ cocci (yes MRSA, no enterococci), anaerobes

25

coverage by vancomycin

aerobic Gr+ cocci

26

1st and 2nd choice for Strep A

1. penicillin
2. 1st gen cephalosporin, macrolide, resp. FQ

27

1st and 2nd choice for Strep pneumoniae

1. penicillin
2. 2 or 3 gen cephal, macrolide, resp FQ, vanco

28

1st and 2nd choice for entercoccus

1. amoxicillin
2. vanco, linolizid

29

1st and 2nd choice for s. aureus (non-MRSA)

1. cloxacillin
2. 1st gen. cephalo, vanco

30

1st and 2nd choice for MRSA

1. blood - vanco, skin- clindamycin

31

Choices for typical enteric pathos (E.coli, proteus, klebsiella)

1. FQ
2. 3rd gen cephalo
3. amoxicillin-clav

32

choices for H. influenzae, moraxella

1. amoxicillan
2. cephalo - 3rd gen
3. resp FQ

33

choices for neisseria meningitidis and gonorrhea

1. 3rd gen cephalo (ceftriaxone)
2. add azithromycin or doxicylin for gon

34

drugs for chlamydia trachomatis and mycoplasma pneumoniae

1. azithromycin
2. doxicycline

35

drugs for bacteroides and other oral and gut anaerobes

metronidazole

36

drugs for C.diff

metronidazole

37

8 issues to think about when choosing the meds

1. local resistance patterns
2. recent AB use
3. co-morbidities that may alter
4. if the patient is very sick
5. cost
6. safety issues
7. tissue penetration
8. cidal vs .static
9. evidence from randomized trials

38

what to do when culture is returned

narrow the spectrum

39

go through the samples

now

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