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Flashcards in Intro to mycology Deck (27):
1

outer features of fungi

1. rigid cell wall
2. cytoplasmic membrane

2

2 mut. requirements for fungi

1. aerobic
2. exogenous nutrient source

3

3 classes of fungi

1. yeasts
2. moulds
3. dimorphic

4

features of yeast

- single cell sometimes with capsule
- divided by mitosis with daughter cell

5

features of moulds

1. made up hyphae - septate or aseptate

6

2 types of hyphae and purpose

1. aerial - reproduction
2. vegetative - provide nutrients

7

what is important about aseptate hyphae

must not grind up for samples

8

when are two dimorphic forms seen

1. yeast form - in vivo or at 37 in vitro
2. mould form - at 22-25deg

9

important endemic dimporphic fungi

blastomyces

10

2 main portals of entry of fungi

1. breach of barriers - lines, burns, cuts
2. inhalation of conidia

11

2 main immune mechanisms to fight fungi

1. non-specific inflammatory rxns - neutophil phago andkilling
2. cell mediated - T-cell CMI

12

4 classes of fungal infections

1. mucocutaneous
2. superficial
3. subcutaneous
4. systemic

13

pathogen in mucocutaneous

c. albicans

14

2 common mucocutaneous

1. thrush
2. diaper dermatitis

15

what are superficial infections

tinea, ringworm - dermatophytosis

16

where does superficial infect

keratinized tissue, because it eats keratin

17

what causes Sx in superficial

inflammation and allergic rxn

18

3 general epidemiologic groups of superfical

1. geophilic
2. zoophilic
3. anthopopohilic

19

2 classes of subcutaneous mycoses

1. chromoblastomycoses and mycetomas
2. sporothrix schenkii

20

what does chromoblastomycoses cause

soil moulds that cause chronic noduclar lesions

21

what does mycetomas cause

black moulds - causes sinus tract and dicharge of visible grains

22

what happens in blastomyces infection

inhale condidia from environment
- colonization in nose and sinuses

23

what is lab hazard in blastomyces

need to be careful to not inhale

24

organisms of systemic fungal infections

opportunistic mycoses - anything that can grow at 37 in an immunocompromised person

25

3 common opportinisitic mycoses

1. candida albicans
2. cryptococcus neoformans
3. asperilligus

26

keys to specimen collection

1. notify lab if dimoprphic suspectes
2. ensure rapid delivery so not overgrown
3. clean with alcohol and scrape outer edge away tp get to the good stuff

27

general principles of mgmt of fungus

1. correct contributing factors - clean feet
2. muco and cutaneous often respond to topical
3. give systemic for systemic infections

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