Insulin resistance + metabolic syndrom Flashcards Preview

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Flashcards in Insulin resistance + metabolic syndrom Deck (14):
1

5 definitions of metabolic syndrom

1. waist > 102men and 88 women
2. TG > 1.7
3. HDL < 1 men and 1.3 women
4. BP > 135/85
5. glucose >6.9

2

differences for men and women in metabolic (2)

waist and HDL

3

5 additional features of metabolic

1. high uric acid
2. high PAI-1 (clotting)
3. high IGF-1 and low binding proteins
4. low adiponectin
5. high CRP (inflammation)

4

2 main types of problematic ectopic fat

1. liver- steatohepatitis
2. muscle - intramyocellular

5

what happens to metabolic folk in stress

more sensitive - leads to high cortisol and insulin resistance

6

2 consequences of high calories

1. high insulin
2. high IGF-1

7

2 consequences of high insuling resitance

1. high BMI
2. less excercise

8

3 cancers related to high BMI and low excercise

1. colon
2. breast
3. prostate

9

4 steps to liver pathology and their markers

1. normal liver (high insulin, high hlucose, high TG)
2. non-acl fatty liver (high ALT, maybe AST)
3. Non- alc steatohepatitis (high ALT and AST)
4. cirrosis

10

2 consequences of renal disease

1. high BP
2. high inflammation

11

what is added insult to renal disease in diabetes

high glucose

12

4 steps that make connection between insulin and BP

high insulin>Na reabasorbtion> H2O follows>high BP

13

3 other mechanisms that link insulin and BP

1. SNS activity
2. RAAS activation
3. oxidative stress

14

4 behavioral treatments of metabolic

1. less calories
2. more excercise
3. lower GI foods (beans, monounsat fat)
4. a little alcohol

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