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Flashcards in clinical adrenal Deck (26):
1

2 general presentations of adrenal disorders

1. hormonal
2. mass effect

2

3 hormonal presentations of adrenal

1. overproduction
2. underproduction
3. mixed

3

4 possible overproduction syndromes

1. GC - cushings
2. MC - Conn's
3. Sex - virilization
4. epi - pheochromocytoma

4

disorder of underproduction

addison's

5

disorder of mixed production

CAH

6

3 types of mass effects

1. single
2. multiple
3. hyperplasia

7

Sx of cushings

1. central obesity
2. moon face
3. metabolic syndrome
4. weakness
5. osteoporosis
6. stria (purple)

8

what is lab test for cushings

24hr cortisol test

9

what is used for cushings suppression test

dexamethosone

10

what to look for in supression test

1. ACTH high - secondary (pit) or ectopic
2. ACTH low - adrenal (primary)

11

what are 2 main Sx of hyperaldosteronsim and why?

hypertension -Na
hypokalemia - K excretion

12

what hormones expected to see in hyperaldosteronism (2)

1. high aldosterone
2. low renin

13

what is suppression test for aldosteron

salt load -

14

what hormone to look at to determine where problem is?

renin - high = secondary
renin - low = primary

15

what is most effective drug in primary hyperaldosteronism

Na channel blocker - works at level of kidney - post aldo

16

other medical treatment of hyperaldosterone

aldostreone receptor blocker

17

what is suspect in cases of severe sexual virilization

adrenal carcinoma

18

what to measure in severe virilization

DHEAS - adrenal specific

19

what is pheochromocytoma

high catecholames

20

what are Sx of pheo

3 Ps:pain(head), palpitations, perspiration + hypertension

21

what to measure to confirm pheo

epiner/norepi + metanephrine/noemeta

22

what is preoperative treatment of pheo

a-blocker to help with vasoconsriction, if tachycardic - add B-blocker

23

what is adrenal underproduction

addisons

24

what are Sx of addisons

low BP that DROPs on standing
low Na
low glucose
high K
hyperpigmentation

25

what is first thing to do in hyperadrenal

TREAT via saline and high dose steroids

26

what is test to assess level

ACTH

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