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Flashcards in GI motility Deck (23):
1

what are extrinsic nerves of GI (2)

1. symp
2. para

2

what are intrinsic GI nerves

enteric system

3

how is muscle of esoph different

striated for first 1/3 then transition to smooth later

4

where is myenteric plexus

nerve plexus b/x muscle layers in GI responsible for muscle control

5

what does symp activation do

lower peristalsis and incr. anal tone

6

what is pacemaker of enteric system

ICC - interstitial cells of colal

7

what transmitters inhib and excite SMC

NO, VIP - relax
Ach - excit

8

what causes action potential im SMC

influx of Ca

9

what make SMC slow wave

slow repolarization

10

what is channel on smooth muscle and what does it mean

voltage-sensitive (L-type) Ca channel
- means needs to hit specific voltage threshold and also is long repolarization type

11

2 parts of SMC coupling

1. slow wave
2. action potential (spike)

12

function of slow wave

omnipresent, produces weak contractions, set basic rhythm

13

function of spikes

on top of slow waves, force of contraction based on number and amp of spikes

14

3 types of esoph. peristalisis and what

1. primary - init by swallow - all along esoph
2. secondary - init by local distension- all along SMC portion
3. tertiary - spontaneous in distal - clearance - often dysfunctional

15

3 things to diff. in oropharyngeal vs. esophageal dysphagia

1. init of swallow
2. choking/cough
3. location of holdup

16

4 ways to differentiatie b/w dysmotility and obstruction

1. inermittent vs. persisitent and progressive
2. liquid and solid vs. solid only
3. temp/stress vs. bread meat
4. assoc. medical illnesses

17

5 alarm signs in dysphagia (cancer)

1. rapid progression and weight loss
2. bleeding
3. vomiting
4. odynophagia
5. age

18

2 types of mechanical lesion

1. intrinsic - CA, diverticula, stricture, rings
2. extrinsic - large aorta, mediastinal mass

19

3 motor functions of somach

1. take in food (relax)
2. trituration - much up food
3. emptying into pyloris

20

how is peristalsis initiated

1. local distension leads to asc. exitation (ach) and descending relaxation (NO)

21

what are 3 phases of contraction

1. irregular during eating
2. quescent contraction when fasting
3. housekeeping push through every 1.5 hours wehn fasting

22

3 phases of colonic peris

1. early segmenting, non-peristalsis to slow fecal stream and absorb water
2. transverse - occasional to push stool forward
3. desceding - rare mass movement

23

3 conceptual types of constipation

1, not enough content
2. not moving
3. not coming out

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