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Flashcards in CSF and BBB Deck (18):
1

what is Fx of CSF

bouyancy to prevent BV and N compression and prevent bouncing around

2

what is CSF derived from and how often

from blood and cleared 3x per day

3

what is lining of ventricles and central canal

ependyma

4

what are 2 components of BBB

1. blood ISF barrier
2. blood CSF barrier

5

what creates BBB-ISF barrier

tight jcts between endothelial cells of the capillaries mean all must pass through endothelial cells

6

what can pass though an endothelial cell

water, gas, lipid solubles, small molecules

7

what forms the blood CSF barrier

choroid plexus

8

what does choroid plexus do

secretes CSF into vent. space

9

what is CP located

in lat, 3 and 4 ventricles

10

what is a choroid plexus made up of

blood vessel with choroid ependymal cells overlaying it

11

what is BBB in CSF

fenestrated caps., but ependyma have tight jcts that stop junk from going through

12

what are 3 openings for CSF in 4th vent

1. median apeture
2. 2 lateral apetures

13

where are 2 places CSF taken back up

1. via arachnoid granulations
2. sheaths of cranial and spinal nerves into lymph system - especially into olfactory tract for mucosa

14

what are 2 types of hydrocephalus

1. obstructive -blockage
2. communicating - not reabsorbing

15

what are features of 2 types

1. obstructive - location indicated by where the vent. is enlarged
2. comm. - all vents enlarged

16

what are causes of comm. hydrocephalus

1. agenisis of arach villi
2. blocak age of villi
3. blockage in subarachnoid space

17

what happens is BBB breaks down

fluid goes out more easily and get edema

18

causes of BBB breakdown

1. tumors
2. AVMs
3. inflammation (stroke, MS)

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