BB LAB - Glossary IV

Question 1

reciprocal of the highest dilution that shows a visible reaction

Answer 1

titer

Question 2

inherited characteristic based from gene action

Answer 2

trait

Question 3

administration of blood or its components intravenously

Answer 3

transfusion

Question 4

type of transfusion

blood taken from a patient to be used for same patient

Answer 4

autologous transfusion

Question 5

type of transfusion

transfer of blood directly from one person to another

Answer 5

direct transfusion

Question 6

type of transfusion
used in infants with HDN, it refers to withdrawal of small volume of blood and subsequent replacement with compatible blood

Answer 6

exchange transfusion

Question 7

type of transfusion

transfusion of blood stored in blood bag coming from a homologous donor

Answer 7

indirect transfusion

Question 8

type of transfusion

blood tranfusion in utero

Answer 8

intrauterine transfusion

Question 9

adverse rxn happening to a patient ff tranfusion of a unit of blood or its components

Answer 9

Transfusion reaction

Question 10

batch test that includes ABO, Rh, and antibody screening test

Answer 10

Type and Screen (T/S)

Question 11

set of guidelines developed to protect healthcare workers from exposure to infectious agents

Answer 11

universal precaution

Question 12

vascular skin reaction commonly signalling allergic rxn

Answer 12

Urticaria (hives)

Question 13

refers to type O and type AB individual s who are considered popularly as universal donor and universal recipient respectively

Answer 13

Universality concept

Question 14

ability of red cell to survive in vivo after transfusion

Answer 14

viability

Question 15

plasma cell dyscrasia characterized by excessive production of gamma M globulin

Answer 15

Waldenstrom’s macroglobulinemia

Question 16

colorless crystalline compound widely used as an anticlotting drug

Answer 16

Warfarin

Question 17

anticoagulant drug that acts by inhibiting synthesis of vitamin K dependent factors: II, VII, IX, X

Answer 17

Warfarin

Question 18

meaning of warfarin

Answer 18

Wisconsin Alumni Research Foundation + (Coum)arin

Question 19

examples (?) of warfarin

Answer 19

coumadin
panwarfin
sofarin

Question 20

refers to successive suspension of whole blood with NSS, centrifugation, and finally decanting completely the supernatant fluid. preferably done 3x to remove interfering substances w/c is present in plasma

Answer 20

washing

Question 21

widely used in preparation of red cell suspension

Answer 21

washing

Question 22

weaker variant of D-antigen that is detectable only through indirect antihuman globulin test

Answer 22

Weak D (D^u)

Question 23

classification of Weak D (D^u)

Answer 23

Acquired D^u, Hereditary D^u, D^u variant/Mosaic

Question 24

grade of Weak D (D^u)

Answer 24

high grade low grade

Question 25

grade of Weak D (D^u) | does not require AHG for detection

Answer 25

high grade

Question 26

AHG meaning

Answer 26

Antihemophilic globulin

Question 27

grade of Weak D (D^u) | requires AHG for detection

Answer 27

low grade

Question 28

thick gelatinous substance rich in hyaluronic acid that make up the matrix of the umbilical cord

Answer 28

Wharton's jelly

Question 29

period of time when the disease is present but tested serologically negative

Answer 29

window period

Question 30

soluble haptenic forms of A and B antigens capable of neutralizing their corresponding antibodies

Answer 30

Witebsky substance

Question 31

blood group whose genes are located in the X-chromosome

Answer 31

Xg blood group

Question 32

what antigen is seen in greatest frequency among females than males

Answer 32

Xg^a

Question 33

net negative charge of red cell measured at the surface of shear; if it is reduced, red cells tend to become closer to each other and therefore easier to agglutinate

Answer 33

zeta potential

Question 34

rxn that is influenced by amount of Ag and Ab from the cell-serum mixture; presence of either prozone or postzone often leads to false negative result

Answer 34

Zonal reaction

Question 35

zone (zonal reaction) | zone of antibody excess (happens if more serum is added)

Answer 35

prozone

Question 36

zone (zonal reaction) | zone of antigen excess (happens if red cell suspension is too heavy)

Answer 36

postzone

Question 37

zone (zonal reaction) | zone of maximum or greatest rxn

Answer 37

Equivalence zone

Question 38

mixture of 0.1 M dithiothreitol (DTT) plus 0.1% cysteine-activated papain used to dissociate IgG molecules from erythrocytes showing a + DAT reaction

Answer 38

ZZAP

Question 38

For anti-a and anti-b what is the required potency

Answer 38

1:256

Question 39

LISS Meaning

Answer 39

Low Ionic Strength Saline solution

Question 40

Composition of LISS

Answer 40

0.2% NaCl in glycine

Question 41

If LISS is used, incubation period may be shortened to -- mins

Answer 41

5-15 mins

Question 42

The lower the ionic strength, the --- the rate of antibody association

Answer 42

Higher

Question 43

Polybrene is useful in ID of Ab in what blood group system

Answer 43

Kidd

Question 44

Former name of respiratory distress syndrome

Answer 44

Hyaline Membrane Disease