HEMA LEC 2 - Cell Populations in Diff Lineages Part II

Question 1

Maturation sequence is less well defined

Answer 1

MEGAKARYOCYTIC LINEAGE

Question 2

– first markers of megakaryocytic

differentiation

Answer 2

CD41, CD61

Question 3

=represents early megakaryoblast

Answer 3

CD34+

Question 4

B & T lymphocytes – derived from lymphoid progenitors that express ___ (3)

Answer 4

CD34, TdT and HLA-DR

Question 5

earliest B cell markers (3)

Answer 5

CD19, cytoplasmic CD22, cytoplasmic CD79

Question 6

specific immature B cell marker; eventually froms B cell receptor

Answer 6

Cytoplasmic μ chain

Question 7

first markers of T cell lineage;

Answer 7

CD2, CD7, cytoplasmic CD3

Question 8

can be present in NK cells with CD 56;

Answer 8

CD2, CD7, cytoplasmic CD3

Question 9

can be used to detect NK cell derived neoplasms

Answer 9

CD2, CD7, cytoplasmic CD3