HEMA LEC - Intro Lecture Flashcards Preview

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1

• 2 Types of PMN

o PMN – mature and segmented
o Neutrophilic bands - immature

2

– immature PMN

bands/ Neutrophilic bands

3

o Shift to the left –

immature

4

o Shift to the right -

mature

5


• with bright orange granules filled with antihistamine

Eosinophils

6

caused by bacterial infection

Neutrophilia:

7

long term drug administration

Neutropenia:

8


theoretical/unused, decrease of eosinophil

• Eosinopenia:

9

allergy, parasitism, increase of eosinophils

• Eosinophilia:

10


rare, hematologic disease (leukemia)

• Basophilia:

11

With dark blue granules that obscure the nucleus

basophils

12

• Big round nucleus, thin rim of cytoplasm
• Slightly larger than RBCs

lymphocytes

13

• viral infection

Lymphocytosis:

14

long term drug administration, immunodeficiency

Lymphopenia/lymphocytopenia

15


• Phagocytosis, presentation of epitopes

monocytes

16

• Macrophage in tissues

monocytes

17

• Slightly larger than other WBCs

monocytes

18

rare hematologic disorder

• Monocytosis:

19

theoretical disease of monocytes

• Monocytopenia:

20

• Pieces of a bone marrow cell called megakaryocyte
• Function to stop bleeding by forming a plug and releases coagulation factors (controls hemostasis)
• Forms thrombus (clot)

platelet

21

platelet capable of

adhesion, aggregation, secretion

22

• 2-4u, oval, anucleated, slightly granular

platelet

23

• Reference range of plt

150 – 450 K/cu. Mm

24

• High MPV means

regenerative BM response to platelet consumption

25

inflammation, trauma

Thrombocytosis

26

: consequence of treatment

Thrombocytopenia

27

HEMATOLOGY TESTS/EXAMINATIONS

1. Erythrocyte Sedimentation Rate
2. Reticulocyte Count
3. Peripheral Blood Examination
4. Sickle Cell Testing
5. Osmotic Fragility Test (OFT)
6. Coagulation Tests include

28

6. Coagulation Tests include

a. Prothrombin Time
b. Partial Thromboplastin Time
c. Fibrinogen
d. Factor Analysis

29

ADVANCED HEMA PROCEDURES

1. BM Examination
2. Cytogenic analysis
3. Molecular assay
4. Cytochemical stains (differentiate abnormal cells)
5. Flow cytometry

30

– decreased platelets, patients may have bleeding problems
-associated with dengue

Thrombocytopenia

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