BB LAB - Glossary of Terms

Question 1

fluid obtained from a cyst of a dog tapeworm which can be a source of P1 substance and there can be used to neutralize anti-P1

Answer 1

Hydatid cyst

Question 2

nonpenetrating cryoprotective agent added to protect cells against damage

Answer 2

Hydroxyethyl starch (HES)

Question 3

decrease in body temp

Answer 3

hypothermia

Question 4

reaction of the body to respond and recognize foreign substances

Answer 4

immune response

Question 5

immunologic rxn induced by initial exposure to antigens

Answer 5

primary immune response

Question 6

immunologic reaction induced following a second exposure to an antigenq

Answer 6

secondary immune response

Question 7

also known as anamnestic response

Answer 7

secondary immune response

Question 8

sugar molecule that gives antigen its specificity or identifies it uniquely

Answer 8

immunodominant sugar

Question 9

H antigen specificity, what is the immunodominant sugar

Answer 9

L-fucose

Question 10

A antigen specificity, what is the immunodominant sugar

Answer 10

N-acetyl-D-galactosamine

Question 11

B antigen specificity, what is the immunodominant sugar`

Answer 11

D-galactose

Question 12

any substance capable of stimulating animmune response

Answer 12

immunogen

Question 13

ability of an antigen to stimulate antibody response

Answer 13

immunogenicity

Question 14

syn for antibody

Answer 14

immunoglobulin

Question 15

study of blood-related antigens and antibodies

Answer 15

immunohematology

Question 16

rare dominant gene that inhibits production of all Lutheran antigens

Answer 16

In Lu

Question 17

presence of agglutination or hemolysis in compatibility testing

Answer 17

Incompatible

Question 18

while fetus is in the uterus

Answer 18

in utero

Question 19

in vitro reaction in w/c under certain condition of time and temperature allow antigen-antibody complex to occur

Answer 19

incubation

Question 20

random behavior of genes on separate chromosomes inherited separately from each other

Answer 20

independent assortment

Question 21

passingof one gene from each parent to offspring

Answer 21

independent segregation

Question 22

transfusion administered to a fetus while still in the uterus

Answer 22

intrauterine transfusion

Question 23

number of charged particles in solution

Answer 23

Ionic strength

Question 24

gamma or electron treatment of cellular blood product to prevent transfusion associated graft-vs-host disease (TA-GVHD)

Answer 24

irradiation

Question 25

yellow appearance of skin, sclera of eyes, and body secretions caused by inc bilirubin level

Answer 25

jaundice

Question 26

condition due to inc in unconjugated bilirubin

Answer 26

kernicterus

Question 27

test performed on maternal blood specimen to detect fetal maternal hemorrhage

Answer 27

kleihauer-betke acid elution test

Question 28

ABO antibodies are present in plasma/serum when the corresponding ABO blood antigens are not present on erythrocytes

Answer 28

Landsteiner Law

Question 29

combination of Ab and multivalent Ag to form cross links and result in visible agglutination rxn

Answer 29

Lattice formation

Question 30

seed extract capable of agglutinating red cells carrying the corresponding antigen

Answer 30

lectin

Question 31

agglutinate red cells with A1 antigen

Answer 31

Dolichus biflorus (anti-A1)

Question 32

agglutinate red cells with H antigen

Answer 32

Ulex europaeus (anti-H)

Question 33

agglutinate red cells with N antigen

Answer 33

Vicia graminea (anti-N)

Question 34

agglutinate red cells with M antigen

Answer 34

Iberis amara (anti-M)

Question 35

agglutinate red cells with T antigen

Answer 35

Arachis hypogea (anti-T)

Question 36

agglutinate red cells with Tn antigen

Answer 36

Salvia sclaera (anti-Tn)

Question 37

graph used to predict severity of HDN during pregnancy by evaluation of amniotic fluid

Answer 37

Liley Graph

Question 38

Liley Graph zone | mild or no disease

Answer 38

Zone I

Question 39

Liley Graph zone | Moderate disease

Answer 39

Zone II

Question 40

Liley Graph zone | Severe and life-threatening hemolysis

Answer 40

Zone III

Question 41

location of gene on chromosome

Answer 41

locus

Question 42

condition of an abnormal presence of hmw immunoglobulins

Answer 42

macroglobulinemia

Question 43

replacement of one or more blood volumes w/in 24 hour interval

Answer 43

massive transfusion

Question 44

common drug used in treatment of hypertension

Answer 44

Methyl Dopa (Aldomet)

Question 45

cause of positive DAT

Answer 45

Methyl Dopa (Aldomet)

Question 46

type of agglutination pattern where a population of redcells has agglutinated and remainder of red cells are not agglutinated

Answer 46

Mixed Field Agglutination

Question 47

manner by which a gene is passed from one gen to another

Answer 47

mode of inheritance

Question 48

type of inheritance patterns trait that appears when gene that has been inherited can be found in each gen occurs with equal frequency in males and females ex. most blood group system

Answer 48

autosomal dominant

Question 49

trait manifested by people who are homozygous for alleles | both parents who do not express the trait may be carrier or heterozygous for recessive allele

Answer 49

autosomal recessive

Question 50

ex. Rh negative (dd), Lu (a-b-), Bombay phenotype

Answer 50

autosomal recessive

Question 51

these are traits transmitted to all daughters of affected father but not to sons

Answer 51

sex-linked dominant

Question 52

ex, Xg^a Blood group

Answer 52

sex-linked dominant

Question 53

trait appears much more frequently in males than in females due to inheritance from carrier mothers

Answer 53

sex-linked recessive

Question 54

ex. hemophilia A

Answer 54

sex-linked recessive

Question 55

it is an antigen composed of several units or subpart such as Rho (D) antigen

Answer 55

Mosaic (Du variant)

Question 56

D antigen w/ complete subpart

Answer 56

Rh ABCD

Question 57

D antigen w/ missing A-subpart

Answer 57

Rh aBCD

Question 58

D antigen w/ missing B-subpart

Answer 58

Rh AbCD

Question 59

D antigen w/ missing C-subpart

Answer 59

Rh ABcD

Question 60

D antigen w/ missing D-subpart

Answer 60

Rh ABCd

Question 61

term for womanhaving borne more than one child

Answer 61

multiparous

Question 62

malignant neoplasm of bm characterized by abnormal proteins in plasma and urine

Answer 62

multople myeloma