Flashcards in BB Lec - Current Trends pt 2 Deck (17):
1
There are three commercial systems approved by the FDA for screening platelets for bacterial contamination:
BacT/ALERT (bioMérieux),
eBDS (Pall Corp.),
Scan- system (Hemosystem)
2
Measures bacteria by detecting a change in carbon- dioxide levels associated with bacterial growth
BacT/ALERT
3
This system (for screening platelets for bacterial contamination) provides continuous monitoring of the platelet sample–containing culture bottles, which are held for the shelf-life of the platelet unit or until a positive reaction is detected.
BacT/ALERT
4
culture-based systems
BacT/ALERT and eBDS
5
As the level of bacteria in the platelets at the time of collection can be low, samples are not taken until after at least how many hours of storage
24
6
measures the oxygen content of the air within the sample pouch following incubation for 18 to 30 hours.
eBDS system
7
in the eBDS system a decrease in oxygen level indicates the __
presence of bacteria
8
, is a laser-based, scanning cytometry method.
Scansystem
9
the first rapid test to detect bacteria in WBD platelets
Pan Genera Detection (PGD) test (Verax Biomedical)
10
an immunoassay that detects lipoteichoic acids on gram- positive bacteria and lipopolysaccharides on gram-negative bacteria. Both aerobes and anaerobes are detected.
Pan Genera Detection (PGD) test (Verax Biomedical)
11
are pooled ABO-matched, leukoreduced WBD platelets that have been cultured and are ready for transfusion.
Acrodose platelets
12
Acrodose platelets are produced in a closed system, they can be stored for how many days from collection
5
13
They provide a therapeutic dose equivalent to apheresis platelets and at a lower cost, but they do expose the recipient to multiple donors.
Acrodose platelets
14
Problem with 7 day storage of PLT
Septic transfusion rxns
14
Problem with 7 day storage of PLT
Septic transfusion rxns
15
PASSPORT meaning
Post approval surveillance study of platelet outcomes, release tested
16