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Flashcards in SI LEC - History Deck (58)
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1

when did immunology become an independent subject

1971, International Conference of
Immunology, in USA

2

3 periods in the history of immunology

Experiential Immunology period
Experimental Immunology period
Modern Immunology period

3

period of immunology
the 17th century- the middle of 19th century

experiential period

4

  is a disease that has a high mortality rate or a calamity with widespread and serious consequences for its victims

Plague

5

who introduced variolation in england from turkey

Lady mary wortley montague

6

process of inoculation of small pox to produce immunity

Variolation:

7

who first introduced variolated

chinese medical practitioners

8

He discovered that cowpox vaccination protected against smallpox in 1796 based on the practice of the chinese

edward jenner, english physician

9

A preparation of microbial antigen, often combined with adjuvants, that is administered to individuals to induce protective immunity against microbial infections.

Vaccine:

10

A general term for immunization against infectious diseases, orginally derived from immunization against smallpox which uses the Vaccinia virus.

Vaccination:

11

: inorganic or organic chemicals, macromolecules or entire cells of certain killed bacteria, which enhance the immune response to an antigen

Adjuvants

12

In ancient times,many serious infection diseases,such as smallpox, plague and cholera etc. caused innumerable people dead.
what period

experiential period

13

molecular structure of 2 antigens are almost similar
one antigen will be able to react w/ the same antibody

cross-reactivity/cross reaction

14

types of vaccines (8)
KATVECHS

killed, attenuated, toxoid, subunit, conjugate, experimental, valence, heterotypic

15

type of vaccine
vaccines that are pathogens of other animals that either do not cause disease or cause mild disease in the organism being treated

heterotypic/heterologous/jennerian

16

type of vaccine
not the whole organism but jus the antigenic parts

subunit

17

type of vaccine
weakened organism

attenuated aG

18

type of vaccine
vaccine + another substance

conjugated

19

what period
the middle of 19th century-the middle of 20th century

Experimental Immunology period

20

1st to introduce active immunity

Robert Koch

21

isolated and cultured bacteria successfully

Robert Koch

22

according to him,
----Infectious diseases were caused
by pathogens

Pasteur

23

he produced an anti-cholera live-attenuated vaccine
(old culture of Chicken V.cholera)

Louis Pasteur

24

what substance was used by Louis Pasteur to produced an anti-cholera live-attenuated vaccine

old culture of Chicken V.cholera

25

type of active immunity
Antigen was artificially made

artificial active immunity

26

what kind of immunity was discovered by Pasteur

artificial active immunity

27


The form of adaptive immunity that is induced by exposure to a foreign antigen and in which the immunized individual plays an active role in responding to the antigen.

Active immunity:

28

type of immunity that was discovered In the late eighties of 19th century

passive immunity

29

who introduced passive immunity

roux and yersin

30

---Diphtheria was caused by exotoxin produced by C.diphtheriae
The discovery of diphtheriae antitoxin and bactericidins

roux and yersin

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