Flashcards in BB LEC - ABO Blood System Part 3 Deck (19)
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1
1% to 8% of __ individuals produce anti-A1 in their serum, and
A2
2
22% to 35% of __ individuals produce anti-A1
A2B
3
A subgroup
has more antigenic sites for the H antigen thus giving(+) rxn w/ Anti-H lectin)
A2 CELL
4
A subgroup
(H antigen sites occupied by both A and A1 antigens
A1 CELL
5
small agglutinates w/in predominantly unagglutinated red cells
Mixed field agglutination:
6
The Bombay phenotype was first reported by ___ in 1952 in Bombay, India
Bhende
7
inheritance pattern of Bombay phenotype
autosomal recessive
8
defect in Bombay phenotype
which gene
mutation in FUT1 (H gene) and FUT2 gene
9
antigens of Bombay phenotype
none
10
genotype of Bombay
hh
11
enzymes in serum present in Bombay
A or B depending on ABO genotype
12
Is the Bombay phenotype secretor or not
nonsecretor
13
genotype w/c is least reactive with Anti-H
A1B
14
are those rare phenotypes in which the RBCs are completely devoid of H antigens or have small amounts of H antigen present.
para-Bombay phenotypes
15
Do Bombay and para-Bombay phenotypes have H enzymes
no
16
The genetic basis for the para-Bombays is (2)
a mutated FUT1 (H gene) with or without an active FUT2 gene (Se gene) or a silenced FUT1 gene with an active FUT2 gene.
17
- a rare group 1 discrepancy.
- presence of two cell populations in single individual like in cases of fraternal twins
CHIMERISM
18
when bacterial enzymes (of Proteus vulgaris) modify N-acetylgalactosamine into D- galactose)
ACQUIRED B phenomenon
19
