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Flashcards in bone and ossification histo Deck (53)
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1

makes up the greater portion of the matrix

Inorganic elements – calcium, magnesium, and sodium

2

Ground substance is calcified – becomes hard and brittle

bone

3

organic elements of bone

(collagen, protein polysaccharide and chondroitin sulfate)

4

functions of bone

Internal support of the body
Attachment of muscles and tendons for locomotion
Contains the bone marrows – blood forming elements
Protects vital organs of the cranial and thoracic cavities
For storage of calcium in the body

5

types of bone based on the organization of its type I collagen fibers

lamellar
woven

6

type of bone
collagen fibers are arranged in an irregular feltwork
fabricated during periods of rapid bone growth

woven

7

type of bone
hypercellular, with large osteocytes and lacunae, distributed in a haphazard fashion, long axes follow the direction of the neighboring collagen fibers

woven

8

type of bone
higher mineral content than that of lamellar bone; deposited outside of collagen fibers

woven

9

type of bone
resist forces equally in all directions; weaker, less rigid, more flexible than lamellar bone (greenstick fracture)

woven

10

type of bone
collagen fibers are deposited in parallel arrays

lamellar

11

type of bone
synthesized more slowly, less cellular, smaller osteocytes and lacunae, distributed in a more organized fashion along the more regular collagen lamellae

lamellar

12

type of bone
process of mineralization occurs more slowly and continues long after the organic matrix is initially deposited

lamellar

13

type of bone
has greater rigidity and tensile strength, less elasticity than woven bone.

lamellar

14

FORMS OF LAMELLAR BONES

Cancellous or Spongy bone (substancia spongiosa)

Compact bone (substancia compacta)

15

LONG BONE
– thick walled hollow cylinder w/ a central medullary cavity containing the bone marrow

Shaft

16

LONG BONE
ends of long bones made up of spongy bone covered by a thin cortex of compact bone

Epiphysis –

17

LONG BONE
– separates the epiphysis from the diaphysis

Epiphyseal plate

18

LONG BONE
a transitional region connecting the epiphyseal plate to the diaphysis

Metaphysis

19

long bone
a layer of specialized CT w/ osteogenic potential

Periosteum

20

long bone
a thin cellular layer w/ osteogenic properties covering the marrow cavity

Endosteum

21

Found in the flat bones of the face and skull

Layer of spongy bone between 2 layers of compact bone forming an outer and inner table

diploe

22

bone cells


Osteoprogenitor cells
2. Osteoblasts
3. Osteocytes
4. Osteoclasts

23

type of bone cells
Undifferentiated cells

On free bony surfaces,
endosteum, periosteum,
lining of the Haversian
canal, epiphyseal plate

With pale staining
nucleus and faintly
basophilic cytoplasm

Osteoprogenitor cells

24

type of osteoprogenitor cells
Divide – (bone - forming cells)

osteoblasts

25

type of osteoprogenitor cells
Unite – (bone - destroying cells)

osteoclasts

26

Bone forming cells responsible for the development of the bony matrix

Location: surfaces of developing bones

Arranged in an epitheloid layer of cuboidal cells

osteoblasts

27

Cells of fully formed bones in the lacunae of calcified matrix

An osteoblast is surrounded by bone matrix in its development

Flattened cell body inside the lacunae

osteocytes

28

Giant multinucleated cells closely associated with areas of resorption

Found in shallow concavities of the bone surface called Lacuna of Howship

osteoclasts

29

osteoclasts are found in shallow concavities of the bone surface called

Lacuna of Howship

30

Active in bone resorption


Ruffled border – radial striations found close to the bone

osteoclasts

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