10.28 10.29 General Anesthetics

Question 1

most irritating to lungs / don’t use in pulmonary disease

Answer 1

desflurane

Question 2

hepatotoxic

Answer 2

halothane (if hypoxic, metabolized to reactive chlorotrifluoroethyl free radical)

and methoxyflurane

Question 3

nephrotoxic

Answer 3

methoxyflurane

Question 4

only nephrotoxic if reacts with CO2

Answer 4

sevoflurane

Question 5

hematotoxicity (megaloblastic anemia, peripheral neuropathy, via loss of B12)

Answer 5

nitrous oxide

Question 6

malignant hyperthermia most often associated with what general anesthetic

Answer 6

halothane

Question 7

most cardiotoxic

Answer 7

halothane

Question 8

DOC to induce unconsciousness if have heart problems

Answer 8

etomidate

Question 9

ADR of propofol (used to induce unconsciousness)

Answer 9

decreased systemic blood pressure

Question 10

drugs to induce unconsciousness

Answer 10

barbiurates (ultra short acting ones)

propofol

etomidate

Question 11

for anterograde amnesia

Answer 11

ketamine

benzodiazepines

Question 12

increase blood pressure, heart rate, CO

Answer 12

ketamine

Question 13

good for hypovolemic shock

Answer 13

ketamine

Question 14

emergence phenomena from ketamine is reversed with

Answer 14

midazolam

Question 15

to ease pain

Answer 15

opioids

Question 16

opioids for short surgical procedures

Answer 16

alfentanil

remifentanil

Question 17

drugs to block NM junction

Answer 17

non depol (cisatracurium, pancuronium, vecuronium)

depol (succinylcholine)

Question 18

short acting brbiturates

Answer 18

thiopental

methohexital

thiamylal