7.19 20 Mature B Cell Lymphomas Flashcards

(46 cards)

0
Q

Small Lymphocytic Lymphoma mainly affects what part of body

A

lymph node

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1
Q

Chronic Lymphocytic Leukemia mainly affects what part of body

A

blood

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2
Q

involves autoimmune hemolytic anemia

A

CLL/SLL

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3
Q

Richter syndrome

A

CLL/SLL transformation to Diffuse Large Cell Lymphoma

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4
Q

t(11;14)

A

mantle cell lymphoma

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5
Q

mantle cell lymphoma translocation

A

t(11;14)

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6
Q

can involve GI tract w/ lymphomatous polyposis

A

mantle cell lymphoma

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7
Q

cyclin-D1

A

mantle cell lymphoma

hairy cell leukemia

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8
Q

can involve middle aged females

A

follicular lymphoma

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9
Q

young boys with head and neck involvement

A

follicular lymphoma

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10
Q

has a leukemic phase

A

follicular lymphoma

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11
Q

has paratrabecular aggregates

A

follicular lyphoma

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12
Q

cleaved nucleus

A

follicular lymphoma

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13
Q

t(14;18)

A

follicular lymphoma

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14
Q

follicular lymphoma involves what translocation

A

t(14;18)

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15
Q

elderly or immunocompromised patients (EBV related)

A

diffuse large B cell lymphoma (even though EBV is classically associated w/ Burkitt lymphoma)

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16
Q

what mature B cell lymphomas can transform into diffuse large B cell lymphomas

A

CLL/SLL

Follicular lymphoma

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17
Q

involves all organs

A

diffuse large B cell lymphoma

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18
Q

prognosis dependent on DNA microarray

A

diffuse large B cell lymphoma

19
Q

involves prolactin

A

sporadic Burkitt lymphoma

20
Q

EBV

A

Burkitt lymphoma

21
Q

seen in patients from equatorial africa

A

endemic Burkitt lymphoma

22
Q

young boy with jaw mass

A

Burkitt lymphoma

23
Q

Starry sky appearance

A

Burkitt lymphoma

24
CNS involvement
Burkitt lymphoma
25
t(8;14)
Burkitt lymphoma
26
Burkitt lymphoma involves what translocation
t(8;14)
27
c-MYC
Burkitt lymphoma
28
very intense short term chemotherapy
Burkitt lymphoma
29
Hairy Cell Leukemia treatment
deoxycoformycin (purine nucleoside analog)
30
CD103, CD25, CD11c
Hairy cell leukemia
31
Splenomegaly
Hairy cell leukemia
32
fried egg appearance of bone marrow
Hairy cell leukemia
33
spleen with red pulp
Hairy cell leukemia Lymphoplasmacytic lymphoma
34
Waldenstrom Macroglobulinemia
marrow involvement with IgM spike in lymphoplasmacytic lymphoma causes thick blood and visual problems
35
Rouleaux
Lymphoplasmacytic Lymphoma
36
IgM
Lymphoplasmacytic Lymphoma
37
IgG
Plasma Cell Myeloma
38
monoclonal serum proteins
lymphoplasmacytic lymphoma plasma cell myeloma
39
Plasma cell myeloma signs and sxs
CRAB hypercalcemia renal insufficiency anemia bone lesions
40
most common lymphoid tumor in Af Am
plasma cell myeloma
41
If suspect plasma cell myeloma, order
SPEP and UPEP (serum and urine protein electrophoresis)
42
CD38, CD138
plasma cell myeloma
43
renal function correlates w/ prognosis
plasma cell myeloma
44
Bcl2
Follicular lymphoma
45
Associated with Hep C
Lymphoplasmacytic lymphoma