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From Flashcardlet > 6.16 muscle path > Flashcards

6.16 muscle path Flashcards

(61 cards)

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0
Q

Fiber type grouping

A

Neurogenic atrophy

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1
Q

Angular, atrophic, esterase positive

A

Neurogenic atrophy

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2
Q

Target fibers

A

Neurogenic atrophy

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3
Q

DMD inheritance

A

X linked

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4
Q

BMD inheritance

A

X linked

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5
Q

DMD characterized by

A

Absence of dystrophin

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6
Q

Absence of dystrophin

A

DMD

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7
Q

BMD distinguished by

A

Decreased dystrophin

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8
Q

Decreased dystrophin

A

BMD

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9
Q

Pseudo hypertrophy of calf muscles

A

DMD

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10
Q

Die from respiratory insufficiency

A

DMD

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11
Q

Myotonic dystrophy inheritance

A

AD

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12
Q

Shows anticipation

A

Myotonic dystrophy

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13
Q

Tetra nucleotide repeat

A

Type 2 myotonic dystrophy

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14
Q 
Atrophy of face
Cataracts
Frontal balding
Gonadal atrophy
Cardiomyopathy
A

Myotonic dystrophy

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15
Q

Sustained involuntary contraction

A

Myotonia

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16
Q

Increased internal nuclei

A

Myotonic dystrophy

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17
Q

Ring fibers

A

Myotonic dystrophy

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18
Q

Malignant hyperthermia with anesthesia

A

Ion channel myopathies

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19
Q

Tubular aggregates

A

Ion channel myopathies

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20
Q

Central cores (decr staining inside hole)

A

Central core disease - a congenital myopathy

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21
Q

Nemaline rods

A

Nemaline rod myopathy - a type of congenital myopathy

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22
Q

Joint contracture a (arthrigryposis)

A

Congenital myopathies

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23
Q

Will improve with age

A

Congenital myopathies

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24
Grouped based on pathological findings
Congenital myopathies
25
Hepatic enlargement
Glycogenoses
26
Hypoglycemia
Glycogenoses
27
Muscle cramps after exercise
Glycogenoses
28
Defect in acid maltase
Pompe (a glycogen storage disease)
29
Defect in myophosphorylase
McArdle (glycogen storage disease)
30
Vacuoles and glycogen
Pompes
31
Involves brain and skel m
Mitochondrial myopathies
32
Maternally inebriated
Mitochondrial myopathies
33
Weak extraocular muscles
Mitochondrial myopathies
34
Rhabdomyolysis
Mitochondrial myopathies
35
Ragged red fibers
Mitochondrial myopathies
36
Para crystalline inclusions
Mitochondrial myopathies
37
Immunosuppressive therapy useful in
Polymyositis | Dermatomyositis
38
Inflammatory myosotis most in female adults
Polymyositis
39
CD8 T cells
Polymyositis
40
Within endomysium and in muscle fiber
Polymyositis
41
Heliotrophic rash
Dermaomyositis
42
Rash on upper eyelids and peri orbital edema
Dermatomyositis
43
Grotton lesions
Dermatomyositis
44
Erythematous scaling rash on knuckles
Grotton lesions seen in dermatomyositis
45
Increased risk of breast and colon cancer
Dermatomyositis
46
Polymyositis that can occur in children
Dermatomyositis
47
B cells and CD4 T cells
Dermatomyositis
48
Perifascicular atrophy (outside border of muscle fiber)
Dermatomyositis
49
Distal muscles
Inclusion body myositis
50
Inflammatory Usually older adults
Inclusion body myositis
51
Inflammatory myositis that doesn't respond to corticosteroid therapy
Inclusion body myositis
52
Rimmed vacuoles
Inclusion body myositis
53
Tubulofilamentous inclusions
Inclusion body myositis
54
Binge drinking alcohol
Rhabdomyolysis
55
Myoglobinuria
Rhabdomyolysis
56
All muscles degenerate at one time
Rhabdomyolysis
57
Type 2 fiber atrophy
Steroid myopathy
58
Vacuolar myopathy
From chloroquine and colchicine
59
Non specific myopathic changes
Statins
60
Mitochondrial myopathy caused by drug..
HIV drugs

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