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From Flashcardlet > 8.2 Nephrotic > Flashcards

8.2 Nephrotic Flashcards

(25 cards)

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1
Q

large, hypercellular, lobular glomeruli

A

membranoproliferative glomerulonephritis (MPGN)

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2
Q

C3 only

A

membranoproliferative glomerulonephritis (MPGN)

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3
Q

double GBM / double contour / tram track

A

membranoproliferative glomerulonephritis (MPGN)

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4
Q

tubuloreticular inclusions on EM

A

HIV associated nephropathy (subset of collapsing glomerulopathy which is a subset of FSGS)

lupus nephritis

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5
Q

subepithelial deposits

A

membranous nephropathy

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6
Q

subendothelial deposits

A

MPGN type I

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7
Q

intramembranous deposits

A

MPGN type II (dense deposit disease)

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8
Q

ribbon-like

A

MPGN type II (dense deposit disease)

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9
Q

responsive w/ steroids

A

minimal change disease

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10
Q

foot process effacement

A

minimal change disease

FSGS

(membranous nephropathy)

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11
Q

IgG and C3

A

membranous nephropathy (granular deposits)

RPGN type I: anti-glomerular BM - but w/ linear deposits

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12
Q

IgM and C3

A

FSGS

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13
Q

C3 (may have IgG, C1q, C4)

A

MPGN - type I

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14
Q

Kimmelstiel Wilson nodules (nodular glomerulosclerosis)

A

diabetic nephropathy

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15
Q

hyalinizing arteriosclerosis

A

diabetic nephropathy

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16
Q

C3 ONLY, as mesangial rings (neg for IgG, C1q, C4)

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A

MPGN - type II

17
Q

thick GBM

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A

diabetic nephropathy

18
Q

thick glomerular capillary loops

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A

membranous nephropathy

19
Q

basement membrane spikes on silver stain

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A

membranous nephropathy

20
Q

diffuse effacement of foot processes only on EM

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A

minimal change disease

21
Q

nephrin gene mutation

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A

congenital nephrotic syndrome (Finnish type)

22
Q

lipoid nephrosis also called

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A

minimal change disease

23
Q

hyalinosis and sclerosis

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A

focal segmental glomerulosclerosis

24
Q

genetic changes in nephrin, podocin, TRPC6, CD2AP

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A

focal segmental glomerulosclerosis

minimal change disease

25
cystic dilatation of tubule segments filled w/ protein, inflammation, fibrosis
HIV associated nephropathy (subset of collapsing glomerulopathy)

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