Wys 2

Question 0

What are the 2 ends of actin called and which one is fast/slow growing?

Answer 0

Pointed (-) end slow growing

Barbed (+) end fast growing

Question 1

3 types of cytoskeletons and size

Answer 1

Microfilament (6 nm)
Intermediate filament (10 nm)
Microtubule (24 nm)

Question 2

4 steps of actin polymerization

Answer 2

Activation
Nuclear job
Elongation
Annealing

Question 3

Reagents that disrupt actin filaments

Answer 3

Cytochalasin
Latrunculin
ATP depression

Question 4

Structure of myosin II

Answer 4

6 polypeptide chains
2 heavy chains
2 sets of light chains

Question 5

Microfilaments contain tracks for

Answer 5

Myosin

Question 6

Microtubules contain tracks for

Answer 6

Kinesin

Dynein

Question 7

Which microtubule subunit hydrolyzes and exchanges GTP?

Answer 7

β

Question 8

Which microtubule subunits bind GTP?

Answer 8

α

β

Question 9

What are protofilaments made of

Answer 9

α and β subunits

Question 10

How many protofilaments form a tube?

Answer 10

13

Question 11

+ end of protofilament is what subunit?

Answer 11

β

Question 12

What is dynamic instability

Answer 12

Alternating between growing and shrinking states of a microtubule

Question 13

Blunt ends associate with what bound to the β tubulin?

Answer 13

GTP

Question 14

What protein is responsible for anterograde transport?

Answer 14

Kinesin

Question 15

What protein is responsible for retrograde transport?

Answer 15

Dynein

Question 16

Structure of centrosome

Answer 16

9 microtubule triplets