3.1 neoplasms

Question 0

New growth

Answer 0

Neoplasm

Question 1

Swelling or distention

Answer 1

Tumor

Question 2

Disorder of cell growth triggered by mutations affecting a single cell and it’s clonal progeny

Answer 2

Neoplasm

Question 3

2 basic components of tumors

Answer 3

Clonality (entire population arises from one cell)

Supporting stroma

Question 4

Leiomyoma

Answer 4

Benign, from smooth muscle

Question 5

Normal tissue in an abnormal location

Answer 5

Choristoma

Question 6

Mass of disorganized but mature specialized cells (is normal tissue in it’s normal location, but just overgrown and disorganized)

Answer 6

Hamartoma

Question 7

Abundant collagenous stroma in response to tumor growth and invasion

Answer 7

Desmoplasia

Question 8

A macroscopically visible projection above a mucosal surface

Answer 8

Polyp

Question 9

The extent to which neoplastic cells resemble comparable normal cells

Answer 9

Differentiation

Question 10

Lack of differentiation

Answer 10

Anaplasia

Question 11

Variation in cell size and shape

Answer 11

Pleomorphism (a feature of malignant neoplasms)

Question 12

Darker cells

Answer 12

Hyperchromasia (a feature of malignant neoplasms)

Question 13

Increased nucleus to cytoplasm ratio is a feature of

Answer 13

Malignant neoplasia

Question 14

Barrett esophagus example of

Answer 14

Esophageal metaplasia

Question 15

Disordered growth
Not malignant
May progress to cancer

Answer 15

Dysplasia

Question 16

Rate of tumor growth dependent on

Answer 16

Doubling time of tumor cells
Fraction of cells in replicative pool
Rate at which cells shed or die

Question 17

Growth fraction

Answer 17

Proportion of cells in a tumor population that are in the proliferation pool (20% or less in most tumors)

Question 18

What factor has an effect on susceptibility to cancer chemo

Answer 18

Growth fraction

Question 19

Tumor implant that is discontinuous with the primary tumor

Answer 19

Metastasis

Question 20

Penetration of tumor into a natural open space

Answer 20

Direct seeding

Question 21

Epithelial malignancies spread via

Answer 21

Lymphatics (lymphatic spread)

Question 22

Mesenchymal malignancies spread via

Answer 22

Blood (hematogenous spread)

Question 23

Treatment of what cancers is highly dependent on how it’s classified

Answer 23

Leukemia

Lymphoma

Question 24

Benign epithelial neoplasms are called

Answer 24

Adenomas

Question 25

Malignant epithelial neoplasms are called

Answer 25

Carcinoma

Question 26

Benign mesenchymal neoplasms end in

Answer 26

-oma

Question 27

Malignant mesenchymal neoplasms end in

Answer 27

-sarcoma

Question 28

What organ is frequently affected in leiomyoma/leiomyosarcoma

Answer 28

Uterus

Question 29

Benign skin neoplasm

Answer 29

Nevus (mole)

Question 30

Malignant skin neoplasms

Answer 30

Melanoma

Question 31

Benign placenta neoplasm

Answer 31

Hydatidiform mole

Question 32

Malignant placenta neoplasm

Answer 32

Choriocarcinoma

Question 33

"-blastoma" refers to

Answer 33

Embryonal tumors

Question 34

Malignant renal neoplasm common in children

Answer 34

Wilms tumor