PH Lecture 16 Flashcards
(13 cards)
Requirements of screening test
1) quick easy cheap
2) safe
3) sensitivity specificity ROC
Requirements of disease for screening
1) serious outcome
2) effective therapy
3) understand disease
4) high prevalence
3 biases when evaluating screening tests
Volunteer bias
Lead time bias
Length bias
What is lead time bias
Perception that a person lived longer because they were screened earlier
What is length bias
Making false conclusions because it’s easier to capture slow/long diseases than short/fast diseases
Length bias is similar to what other bias?
Neyman bias
Requirements to do diagnostic test
1) follow up available for positive results
2) treatment available
3) can handle positive result
Multiphasic screening
- what is it
- pro
- con
Screening for many diseases in one visit
Pro: efficient
Con: higher risk of false positives
What is not considered to be a periodic health exam?
Infants
Elderly
Pregnant women
The USPSTF has recommendations for what levels of prevention?
Primary
Secondary
USPSTF internal validity ranking
I - randomized control trial II1 - controlled trials without randomization II2- cohort or case control II3 - time series or uncontrolled III - anecdotal
USPSTF quality of evidence grade
Good
Fair
Poor
USPSTF strength of recommendation
A - strongly recommends B - recommends C - not recommend D - against I - insufficient
