6.12 anxiolytics

Question 0

Ultra short acting benzo

Answer 0

Triazolam

Question 1

Long acting benzo metabolite

Answer 1

Desmethyldiazepam

Question 2

Treats benzo withdrawal

Answer 2

Clonazepam

Question 3

Reverses benzo and Z drug overdose

Answer 3

Flumazenil

Question 4

Benzo GABA-A antagonist

Answer 4

Flumazenil

Question 5

Benzo CIs

Answer 5

Activities that require mental alertness

History of drug abuse

Pregnant or breastfeeding

Question 6

Z drugs

Answer 6

Zolpidem

Zaleplon

Question 7

Approved for generalized anxiety disorder

Answer 7

Buspirone

Question 8

Long acting benzos

Answer 8

Chlordiazepoxide
Diazepam
Flurazepam

Question 9

Short acting benzos

Answer 9

Alprazolam
Lorazepam
Oxazepam
Temazepam

Question 10

Useful for elderly and those with liver dysfunction

Answer 10

Ultra short acting and short acting benzos

Question 11

Increase frequency of channel opening caused by GABA binding

Answer 11

Benzodiazepine

Question 12

Increase duration of channel opening

Answer 12

Barbiturates

Question 13

What is clonazepam

Answer 13

Medium acting Benzo for Benzo withdrawal

Question 14

Metabolic difference between long acting and short acting benzos

Answer 14

long acting uses phase I oxidation

short acting uses phase II glucuronidation (no desmethyldiazepam metabolite)

Question 15

What drugs inhibit oxidative metabolism and therefore increases half life of BZDs

Answer 15

cimetidine
disulfiram
isoniazid
estrogen
OCPs

Question 16

What decreases BZD levels via enzyme induction

Answer 16

Rifampin

tobacco

Question 17

What decreases BZD absorption

Answer 17

food

antacids

Question 18

SSRIs are first line treatment for

Answer 18

panic disorder
Social anxiety disorder
OCD
PTSD

Question 19

First line for GAD

Answer 19

BZD

Buspirone (anxiolytic)