Psych Exam 1 Flashcards

(90 cards)

0
Q

Down’s syndrome facial features

A

Flat nasal bridge

Upward slanted palpebral fissures

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1
Q

Leading cause of mental retardation

A

Down’s syndrome

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2
Q

Beta amyloid encoded on what chromosome

A

21

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3
Q

Down’s syndrome prone to what disease

A

Alzheimer’s

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4
Q

Small hands and feet related to

A

Pradeep Willi

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5
Q

Moderate MR chromosome 15

A

Prader Willi

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6
Q

Severe MR chromosome 15

A

Angelman

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7
Q

Second leading cause of mental retardation

A

Fragile X

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8
Q

Von recklinghausen also called

A

Neurofibromatosis

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9
Q

Neurofibromatosis also called

A

Von recklinghausen

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10
Q

Neurofibromatosis chromosome

A

17

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11
Q

Chromosome 17 deficit

A

Neurofibromatosis

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12
Q

Huntingtons disease involves death of

A

GABA & ACh

These both control dopamine, so when lower GABA and ACh, higher dopamine

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13
Q

Familial risk has higher association in _____ vs schizophrenia

A

Bipolar disorder

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14
Q

What disorder has components of antisocial behavior

A

Klinefelter syndrome

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15
Q

Hypogonadism, scant body and pubic hair, tall

A

Klinefelter

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16
Q

Shield chest, webbed neck, congenital heart defects

A

Turner

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17
Q

What disease makes you susceptible to depression

A

Turner

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18
Q

Tourette’s chromosome

A

18

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19
Q

Tourette’s get motor tics by age

A

7

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20
Q

Tourette’s get vocal tics by age

A

11

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21
Q

Neurotransmitter defects in Tourette’s

A

Too much dopamine in nigrostriatal pathway

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22
Q

Obscene words

A

Coprolalia

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23
Q

Repeat own words

A

Palilalia

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24
Repeat other words
Echolalia
25
Normal development for 6 months then decline
Rett's
26
Stereotypic hand movements
Rett's
27
75% have abnormal EEG and seizures
Rett
28
Wilson's disease chromosome
13
29
Chromosome 13 defect
Wilson's
30
Mechanism of Wilson's disease
Decreased production of ceruloplasmin therefore decrease copper in bile, so copper accumulates in liver urine and cornea
31
Copper accumulates where in Wilson's disease
Liver Urine Cornea
32
Wing beating tremor
Wilson's disease
33
Kayser Fleischer rings
Wilson's disease
34
Autism chromosome
7
35
Chromosome 7
Autism
36
Decreased number of ourkinje cells in cerebellum
Autism
37
Autism has decreased purkinje cells in
Cerebellum
38
Rehab for stroke is similar for treatment of
Autism
39
Excitatory neurotransmitters
Dopamine NE Glutamate
40
Inhibitory neurotransmitters
GABA Serotonin Acetylcholine
41
Norepinephrine goes with
Serotonin
42
Dopamine goes with
Acetylcholine
43
Major excitatory NT
Glutamate
44
Most abundant amino acid in CNS
Glutamate
45
Norepinephrine cell bodies
Locus ceruleus
46
Serotonin cell bodies
Raphe nucleus
47
ACh cell bodies
Nucleus basalis of meynert
48
Dopamine cell bodies
Substantia nigra and ventral tegmental areas
49
Role of hippocampus
Memory
50
Role of amygdala
Emotional relevance to memories | Response to stress (fear, anger, aggression)
51
Kluver Bucy syndrome
Amygdala lesion | Decreased fear response
52
Role of hypothalamus
Hormone secretion Eat Sleep Autonomics
53
Role of cingulate gyrus
Focus
54
Frontal lobe function
Executive function Insight Discretion oriented decisions
55
Frontal lobe left vs right
Left - positive emotions | Right - negative (dysphoric) emotions
56
Parietal lobe function
Temporospatial | Number crunching
57
Temporal lobe function
Language | Posterior receiving, anterior expressing
58
Parts of limbic system
``` Hippo Amygdala Thalamus Hypothalamus Fornix Septum Cingulate gyrus ```
59
Alzheimer's genes
APOEe2 good 2 go | APOEe4 done 4
60
Most common dementia
Alzheimer's
61
2nd most common dementia
Vascular dementia
62
Pick's disease / frontotemporo dementia
Accumulation of tau proteins
63
Lewy body dementia
Dementia plus - motor of Parkinson's - fluctuating cognition - visual hallucinations
64
Dysthymia
Chronic low grade depression
65
Melancholia
Organic depression | Sleep disrupted
66
Incidence of depression
15%
67
Depression and gender
Males more
68
SIGECAPS
``` Sadness Interest Guilt Energy Concentration Appetite Panic Pissed off Sleep ```
69
Antidepressant meds
SSRI SNRI TCA MAOI
70
Mechanism of TCA
Block NE and serotonin transport
71
Fluoxetine
SSRI
72
Fluvoxamine
SSRI
73
Sertraline
SSRI
74
Paroxetine
SSRI
75
Citalopram
SSRI
76
Escitalopram
SSRI
77
Duloxetine
SNRI
78
Venlafaxine
SNRI
79
Desvenlafaxine
SNRI
80
Milnacipram
SNRI
81
Amitriptyline
TCA
82
Imipramine
TCA
83
Doxepin
TCA
84
Bupropion
NDRI
85
Meds for bipolar
``` Lithium Anticonvulsants - carbemazepine (tegratol) - valproic acid (depakene) - lamotrigine (lamictal) ```
86
Mood stabilizers for bipolar all modulate what NT
Glutamate
87
What is not a parasomnia
Restless leg syndrome
88
Circadian pacemaker
Suprachiasmatic nucleus of hypothalamus
89
To diagnose narcolepsy (sleep labs)
All night polysomnography Then Multiple sleep latency test