Antimycobacterial drugs Flashcards
(5 cards)
0
Q
Activated by KatG (catalase peroxidase)
A
Isoniazid
1
Q
First line drugs that are also prodrugs
A
Isoniazid
Pyrazinamide
2
Q
Inhibits DNA dependent RNA polymerase
A
Rifampin
3
Q
Active drug of isoniazid
A
Nicotinoyl radical or isoniazid
4
Q
What does activated isoniazid do
A
Inhibits InhA and KasA which are used in synthetic pathway of mycolic acids
