Rajendran Flashcards
(8 cards)
What is pancreatic insufficiency characterized by?
Decreased secretion of digestive enzymes and HCO3-
Advantages of having pH at nearly neutral values in duodenal lumen
Inactivates pepsin (prevents damage)
Provides best pH for pancreatic and brush border enzymes
Increase solubility of bile acids as fatty acids
What causes pancreatic insufficiency?
Chronic pancreatitis
Can biliary tract disease be related to pancreatic insufficiency?
No! Biliary tract disease is associated with acute pancreatitis which does not cause pancreatic insufficiency
What becomes harder to digest if you have pancreatic insufficiency?
Macronutrients
Vitamin B12
What stimulates CCK release in the intestinal phase of pancreatic secretion?
Long fatty acids
What 3 things go on in the intestinal phase of pancreatic secretion?
Vago-Vagal (enterohepatic) reflex
CCK release
Secretin released
What is a good treatment for pancreatic insufficiency?
Increase intragastric pH and coat enzyme pills to increase enzymes in intestine
