Thalamus and Sleep Flashcards
(28 cards)
What are the intralaminar nuclei
Centromedian
Parafascicular
3 groups of thalamic nuclei
Intralaminar
Principal
Reticular
Intralaminar nuclei inputs and outputs
Input: pallidum, cerebellum, ALS
Output: striatum
Intralaminar nuclei reciprocal connections
Frontal
Limbic
Parietal
Intralaminar nuclei functions
Motor planning
Pain perception
What are the 2 types of principal nuclei?
Relay and associational nuclei
What are the 6 relay nuclei?
Motor: VA, VO, VL
Sensory: VPL/VPM, MGN, LGN
What are the 5 associational nuclei?
Anterior Lateral dorsal Mediodorsal Pulvinar Lateral posterior
The relay nuclei are reciprocally connected with
Primary and unimodal cortical areas
The associational nuclei are reciprocally connected with
Unimodal and multimodal associational cortical areas
Major neuron in principal thalamic nuclei
Thalamocortical neuron (excitatory glutamatergic)
Principal nuclei have what type of interneurons?
Inhibitory interneurons
Where does the thalamocortical neuron synapse in the cortex?
Middle layer
- 4 if granular
- 3 if agranular
(Some in layer 6)
Mammillary body and hippocampus pathway
Anterior and lateral dorsal
Cingulate cortex
Amygdala, olfactory bulb, olfactory cortex pathway
Medial dorsal
Prefrontal and orbitofrontal
Substantia nigra pars reticularis pathway
Ventral anterior
Prefrontal and orbitofrontal
Globus pallidus pathway
VO
Premotor and supplementary motor area
Dentate and interposed pathway
VL
Motor cortex
Dorsal column nuclei, trigeminal, and spinal cord pathway
VPL/VPM
Somatosensory cortex
Inferior colliculus pathway
MGN
Auditory cortex
Superior colliculus pathway
Lateral posterior and pulvinar
Multimodal associational and visual associational
Retina pathway
LGN
Visual cortex
Thalamus acts as a relay (allows sensory info in) in what states
Awake and attentive
Thalamus acts as pacemaker in what states
Drowsiness
Sleep
Some comas
Absence epilepsy
