6.27 Toxicity of Metals

Question 1

plastics

Answer 1

lead

Question 2

toys

Answer 2

lead

Question 3

lung sxs

Answer 3

mercury
cadmium
Arsenic 
beryllium
chromium
nickel
(everything but lead, mercury salt, and organic mercury)

Question 4

binds SH groups

Answer 4

lead

Question 5

binds sulfur and replaces H in SH

Answer 5

mercury

Question 6

uncouples ox phos

Answer 6

As5+

Question 7

in dental amalgams

Answer 7

mercury

Question 8

3 types of mercury

Answer 8

elemental mercury
inorganic mercury salts
organic (methyl mercury)

Question 9

can get from electroplating

Answer 9

cadmium
nickel
chromium

Question 10

circuit boards

Answer 10

beryllium

Question 11

distributed everywhere

Answer 11

organic mercury

arsenic

Question 12

hepatic elimination

Answer 12

arsenic

Question 13

metabolites are more toxic

Answer 13

arsenic

Question 14

inhaled

Answer 14

lead

mercury

Question 15

goes thru enterohepatic recycling

Answer 15

organic mercury

Question 16

treatment for lead

Answer 16

succimer (mod)
dimercaptol (severe)
EDTA (severe)

Question 17

treatment for lead encephalopathy

Answer 17

dimercaprol then EDTA

Question 18

treatment for elemental mercury

Answer 18

dimercaptol for acute

succimer less severe

Question 19

treatment for inorganic mercury

Answer 19

dimercaptol for acute

succimer less severe

Question 20

Minimaa disease

Answer 20

organic mercury

Question 21

CNS

Answer 21

lead
organic mercury
arsenic (peripheral neuropathy)

Question 22

Mee’s lines

Answer 22

arsenic

Question 23

hypertension

Answer 23

lead

arsenic

Question 24

avoid large predator fish

Answer 24

organic mercury

Question 25

treatment for arsenic

Answer 25

dimercaptol (acute) | succimer (subacute, chronic)

Question 26

osteoporosis

Answer 26

cadmium

Question 27

lung cancer

Answer 27

beryllium chromium nickel arsenic?

Question 28

nasal cancer

Answer 28

nickel

Question 29

wrist drop

Answer 29

lead in adults

Question 30

Fanconi-like syndrome

Answer 30

lead

Question 31

binds ALAD and causes anemia

Answer 31

lead

Question 32

chronic granulomatous disease in lungs

Answer 32

beryllium

Question 33

pressure treated wood

Answer 33

arsenic

Question 34

volcanoes

Answer 34

mercury

Question 35

crosses placenta

Answer 35

lead organic mercury arsenic

Question 36

renal sxs

Answer 36

lead mercury cadmium

Question 37

liver

Answer 37

arsenic

Question 38

nuclear inclusion bodies in renal tubular cells

Answer 38

lead

Question 39

metal binding proteins

Answer 39

metallothioneins transferrin ceruloplasmin ferritin

Question 40

mimicry of essential metals

Answer 40

Cd, Cu, Ni replace Zn | Pb replaces Ca

Question 41

only chelator that crosses BBB

Answer 41

dimercaptol

Question 42

stored in bone

Answer 42

lead