Breast Flashcards
(31 cards)
inflammatory process associated w/ smoking
- dx
- tx
periductal mastitis
surgical excision of abscess
dilated ducts containing debris and histiocytes
mammary duct ectasia
seen in ruptured breast implant
- dx
- histo
granulomatous mastitis
multinucleated giant cell and granuloma
lactating female w/ inflammation
- dx
- cause
- tx
acute mastitis
Staph aureus or strep
drain milk and give ATBs
see dead adipocytes being phagocytized by histiocytes
fat necrosis
3 subcategories of fibrocystic changes
non-proliferative
proliferative without atypia
proliferative with atypia
differentiate florid sclerosing adenosis vs invasive carcinoma
actin stain (confirms presence of myoepithelial cells in florid sclerosing adenosis)
central fibrosis distorting associated benign ductal structures
radial scar / complex sclerosing lesion (part of fibrocystic change - prolif w/o atypia)
peripheral slit-like glandular spaces
atypical ductal hyperplasia (part of fibrocystic change)
looks like lobular CIS but cells don’t fill more than half of acini within a lobule
atypical lobular hyperplasia (part of fibrocystic change)
single filing
invasive lobular carcinoma
can see intracytoplasmic vacuoles (mucin positive)
invasive lobular carcinoma
most common breast cancer
invasive ductal carcinoma
which cancer has greatest chance of mets to CNS
invasive lobular carcinoma
sheets of pleomorphic cells with pushing borders
medullary carcinoma
negative for ER/PR rec, HER2/neu
medullary carcinoma
seen in older women
mucinous (colloid) carcinoma
bland tumor cells in pools of extracellular mucin
mucinous (colloid) carcinoma
tubules w/ angled borders
tubular carcinoma
tear drop / tennis racket
tubular carcinoma
lymphovascular involvement
inflammatory carcinoma
peau d’orange
inflammatory carcinoma
ER/PR positive treated w/
tamoxifen
HER2/neu treated w/
herceptin
