6.4 ADHD Flashcards
(23 cards)
Active isomer of methylphenidate
Desmethylphenidate
Stimulants for ADHD
Amphetamine
Methylphenidate
Mechanism of amphetamines
Inhibit DAT
Inhibit VMAT
Activate TAAR1, +P DAT, reversal of DAT
CI in eating disorders
Amphetamines
CI in moderate to severe HTN
Amphetamines
CI in severe anxiety
Methylphenidate
Antagonized by lithium
Amphetamines
CI in glaucoma
Amphetamines
Methylphenidate
Atomoxetine
What can you use if have glaucoma
Guanfacine
Clonidine
Causes most sleepiness
Clonidine
Doesn’t worsen tics
Antidepressants and anxiolytics such as TCAs, bupropion, buspirone
CI in jaundice
Atomoxetine
Post synaptic alpha 2 receptor agonist
Guanfacine
Clonidine
Also a stimulant for narcolepsy
Modafinil
Causes emotional lability as ADR
Amphetamines
Methylphenidate
Can cause hypotension
Clonidine
Guanfacine
CI in severe psychosis
Methylphenidate
Can worsen tics
Amphetamines
Methylphenidate
What are the amphetamines
Amphetamine
Dextroamphetamine
Lisdexamfetamine
What is the amphetamine prodrug
Lisdexamfetamine
Dysphoria, sleep disturbances, psychomotor changes, and ravenous appetite all caused by
Abrupt discontinuation of amphetamines leading to withdrawal
Can cause sudden unexplained death
Amphetamines
TCAs
Commonly causes anorexia
Amphetamines