Glucose Uptake and Glycolysis Flashcards
(12 cards)
Direction of glucose transport
Blood to cells
Glucose levels maintained at
70-110 mg/dl
What kind of transport is used for glucose?
Passive facilitated
Rate of glucose transport depends on
Glucose use
GLUT isoform
What cells use insulin independent transport?
RBCs, brain, liver
How does insulin independent transport work?
Only occurs when blood glucose conc high (liver GLUT high capacity but low affinity)
What cells use insulin dependent transport?
Muscle
Adipose tissue
How does insulin dependent transport work?
Akt and cbl-p signaling moves GLUT4 from cytoplasmic vesicles to plasma membrane
Where does glycolysis occur?
Cytoplasm of all cells
Glycolysis basic overall reaction
Glucose –> pyruvate
Does glucose get oxidized or reduced?
Oxidized
What are the 3 main stages of glycolysis?
1) priming stage
2) splitting stage
3) oxidation/reduction stage