7.25 Thyroid

Question 1

T3 and T4 are bound to what in plasma

Answer 1

thyroxine binding globulin (TBG)

Question 2

excessive release of preformed thyroid hormones is called

Answer 2

thyroiditis

Question 3

skeletal muscle atrophy

Answer 3

hyperthyroid

Question 4

osteoporosis

Answer 4

hyperthyroid (increased bone resorption)

Question 5

diarrhea

Answer 5

hyperthyroidism

Question 6

thyroid storm most often occurs in people who have what disease

Answer 6

Graves disease

Question 7

patient febrile with tachycardia after surgery or abrupt stop in antithyroid meds

Answer 7

thyroid storm

Question 8

thyroid challenge test

Answer 8

radioactive iodine uptake test

Question 9

diffuse increased uptake of radioactive iodine

Answer 9

Graves disease

Question 10

increase uptake of radioactive iodine in solitary nodule

Answer 10

toxic adenoma

Question 11

decrease uptake of radioactive iodine

Answer 11

thyroiditis

Question 12

tx for hyperthyroidism

Answer 12

propylthiouracil

carbimazole

radioiodine ablation

surgery

Question 13

triad of graves disease

Answer 13

hyeprthyroidism

exophthalmos

pretibial myxedema

Question 14

30 yo female comes in office. Has bruit, wide staring gaze, and a waxy edema over the shin. What does she have?

Answer 14

Graves disease

Question 15

cause of exophthalmos

Answer 15

increase retro-orbital CT volume b/c of

1) T cell infiltration
2) inflammatory edema and swelling of EOM
3) accumulate ECM (GAGs)

Question 16

Graves disease what type of hypersensitivity reaction

Answer 16

type 2

Question 17

what autoantibody is present in Graves disease

Answer 17

thyroid stimulating immunoglobulin (IgG binds TSH receptor and mimics action of TSH)

Question 18

pale colloid with scalloped margins

Answer 18

Graves disease

Question 19

patient has increased T4, decreased TSH. most likely has

Answer 19

Graves disease

Question 20

hypothyroid child

Answer 20

cretinism

Question 21

hypothyroid adult

Answer 21

myxedema

Question 22

most common cause of congenital hypothyroidism

Answer 22

iodine deficiency

Question 23

most common cause of hypothyroidism in iodine sufficient areas

Answer 23

Hashimoto thyroiditis

Question 24

amiodarone can cause (hypo/hyper)

Answer 24

hypothyroidism

Question 25

cretinism usually occurs where

Answer 25

mountainous areas (himalayas, inland china, africa)

Question 26

child with stunted physical and mental growth, coarse facial features, protruding tongue, umbilical hernia

Answer 26

cretinism

Question 27

slow mental and physical activity, depression-like

Answer 27

myxedema (adult hypothyroid)

Question 28

constipation

Answer 28

hypothyroid

Question 29

non pitting edema

Answer 29

hypothyroid

Question 30

coarse facial features

Answer 30

hypothyroid

Question 31

enlarged tongue

Answer 31

hypothyroid

Question 32

deepened voice

Answer 32

hypothyroid

Question 33

gradual thyroid failure from autoimmune destruction of thyroid

Answer 33

hashimoto thyroiditis

Question 34

Hashimoto thyroiditis what type of hypersensitivity reaction

Answer 34

type 4

Question 35

Hashimoto thyroiditis has autoantibodies to

Answer 35

Thyroid peroxidase (TPO) Thyroglobulin (colloid)

Question 36

Hurthle cells

Answer 36

Hashimoto thyroiditis

Question 37

lymphocytes w/ germinal centers

Answer 37

Hashimoto thyroiditis subacute lymphocytic thyroiditis

Question 38

transient thyrotoxicosis and then hypothyroidism

Answer 38

Hashimoto thyroiditis

Question 39

If you have Hashimoto thyroiditis, you are at an increased risk for

Answer 39

Type 1 DM autoimmune adrenalitis SLE Myasthenia Gravis Sjogren's MALT lymphoma thyroid epithelial carcinoma

Question 40

DeQuervian thyroiditis is also called

Answer 40

subacute thyroiditis Granulomatous thyroiditis

Question 41

hypothyroidism post viral inflammatory process like upper reps tract infection

Answer 41

subacute thyroiditis / DeQuervian thyroiditis / Granulomatous thyroiditis

Question 42

lymphocytes, macrophages, plasma cells, multinucleate giant cells around damaged thyroid follicles

Answer 42

subacute thyroiditis / DeQuervian thyroiditis / Granulomatous thyroiditis

Question 43

most common cause of thyroid pain

Answer 43

subacute thyroiditis / DeQuervian thyroiditis / Granulomatous thyroiditis

Question 44

hyperthyroid, then euthyroid

Answer 44

subacute thyroiditis / DeQuervian thyroiditis / Granulomatous thyroiditis

Question 45

painless thyroiditis that causes mild hyperthyroidism (some evolve into hypothyroidism later)

Answer 45

subacute lymphocytic thyroiditis

Question 46

subacute lymphocytic thyroiditis is similar to

Answer 46

postpartum thyroiditis

Question 47

IgG related thyroid disease also called

Answer 47

Reidel thyroiditis / Fibrous thyroiditis

Question 48

extensive fibrosis of thyroid

Answer 48

Reidel thyroiditis / IgG4 related thyroid disease / Fibrous thyroiditis

Question 49

hard, fixed thyroid mass

Answer 49

Reidel thyroiditis / IgG4 related thyroid disease / Fibrous thyroiditis