8.8 Testes

Question 1

undescended testes also called ___

• usually found in what location
• associated with
• treatment

Answer 1

cryptorchidism

within inguinal canal

infertility, testicular tumors

orchiopexy (surgical repositioning) by 1 year-ish

Question 2

hyalinized and thick BM, absence of spermatogenesis, more prominent Leydig cells

Answer 2

cryptorchid testes

Question 3

fibrotic seminiferous tubules

Answer 3

atrophic testes

Question 4

causes of orchitis / epididymitis

Answer 4

children: congenital anomalies, GNR

young men: STDs (chlamydia, gonorrhea)

older men: E. coli, pseudomonas

Question 5

std starts in posterior urethra

Answer 5

gonorrhea

Question 6

bilateral mumps results in

Answer 6

infertility

Question 7

organism starts in epididymis

Answer 7

TB

Question 8

organism starts in testis

Answer 8

syphilis

Question 9

testicular tumors are mostly

- chromosome

Answer 9

malignant mixed germ cell tumors

12, i(12p) - isochromosome of short arm

Question 10

serum tumor markers for testes

Answer 10

HCG

AFP

LDH

Question 11

testicular tumors spread to what LN

Answer 11

para-aortic LN

Question 12

what testicular tumors are radiosensitive and radioresistant

Answer 12

seminomas radiosensitive

nonseminomatous tumors radioresistant (but can use combo chemo)

Question 13

in situ lesion of testes thought to give rise to most germ cell tumors

Answer 13

intratubular germ cell neoplasia (ITGCN)

Question 14

placental alkaline phosphatase

c-KIT (CD117)

Answer 14

seminoma

Question 15

abundant clear cyto and prominent nucleoli with reactive T cells and uniform cells

Answer 15

seminoma

Question 16

3 cell populations, doesn’t met, in older males

Answer 16

spermatocytic seminoma

Question 17

glandular, atypical nuclei, basophilic cyto, frequent mitoses, 30 year old

Answer 17

embryonal carcinoma

Question 18

most common testicular tumor in infants and children

Answer 18

yolk sac (endodermal sinus) tumor

Question 19

have Schiller-Duval bodies (central blood vessel in tumor germ cells) among lace-like pattern

Answer 19

Yolk sac tumor

Question 20

AFP or alpha 1 antitrypsin

Answer 20

yolk sac tumor

Question 21

have syncytiotrophoblasts (make HCG) and cytotrophoblasts with early mets, necrosis, hemorrhage

Answer 21

choriocarcinoma

Question 22

various germ cell layers

Answer 22

teratoma

Question 23

sexual precocity in kids (facial hair) or gynecomastia in adults

Answer 23

Leydig cell tumor

Question 24

crystalloids of Reinke

Answer 24

Leydig cell tumor

Question 25

abundant cyto with eccentric nucleoli

Answer 25

Leydig cell tumor

Question 26

immature seminiferous tubules that may be hormonally active, and may have granulosa (female) cells

Answer 26

Sertoli cell tumor

Question 27

most common testicular tumor in men over age 60 | - usually what type

Answer 27

testicular lymphoma diffuse B cell lymphoma

Question 28

most common lesion of proximal spermatic cord | - associated w/

Answer 28

cord lipoma (not true neoplasm) associated w/ inguinal hernias

Question 29

most common benign paratesticular tumor

Answer 29

adenomatoid tumor

Question 30

most common malignant paratesticular tumor

Answer 30

kids: rhabdomyosarcoma adults: liposarcoma

Question 31

calretinin stain positive

Answer 31

adenomatoid tumor