8.17 Ovaries Flashcards
(22 cards)
signet ring cells in ovary
Krukenberg tumor
mets to the ovary usually originate from what cell type
Mullerian (so from uterus, fallopian tube, CL ovary, peritoneum)
PCOS also called
Stein-Leventhal syndrome
hairy, obese, and infertile
PCOS
large ovaries with thick cortex
PCOS
most common malignant ovarian tumor
serous tumors
mutations in ovarian serous tumors
BRCA 1 and 2
KRAS, BRAF (low grade)
p53 (high grade)
BRCA 1 chromosome
17
BRCA 2 chromosome
13
shiny, looks like fluid filled cyst
serous cystadenoma
his to of serous tumors (benign, LMP, malig)
benign: ciliated columnar epith
LMP: stratified epith, nuclear atypic
malig: destructive stromal invasion
all: psammoma bodies (moreso in LMP and malig)
risk factors for getting mucinous tumors
smoking
KRAS
large gelatinous cysts
mucinous tumors
mucinous ascites
pseudomyxoma peritonei (associated w/ mucinous cystic neoplasms)
blood test used to monitor pts w/ surface epithelial tumors (serous, mucinous)
CA-125
8 year old w/ breast
- dx
- blood test
juvenile granulosa cell tumor
inhibin
can cause endometrial hyperplasia and carcinoma
- dx
- blood test
granulosa-theca tumors
inhibin
solid, hard, grey/white
fibroma / fibroma-thecoma
ovarian fibrothecoma, ascites, hydrothorax
Meigs syndrome
Meigs syndrome
ovarian fibrothecoma, ascites, hydrothorax
fibroma-thecoma associated w/ what skin thing
basal cell nevus syndrome
breast atrophy, amenorrhea, sterility, loss of hair or hirsutism
sertoli-leydig cell tumors
