Chemo drugs 2

Question 0

CNS toxicity

Answer 0

Ifosfamide

Cytarabine

Question 1

Don’t give with p450 inhibitors

Answer 1

Cyclophosphamide

Ifosfamide

Question 2

Not used if have curative intent because of bad toxicity

Answer 2

Erythropoietin

Question 3

Dosing based on GFR

Answer 3

Carboplatin

Question 4

Auditory neuropathy

Answer 4

Cisplatin

Question 5

Hand foot syndrome

Answer 5

5-FU

Sunitinib

Question 6

Affects PNS

Answer 6

Cisplatin
Methotrexate (neurotoxicity)
Vincristine
Paclitaxel (sensory neuropathy)
Docetaxel

Question 7

Menopausal symptoms

Answer 7

Tamoxifen

Anastrozole

Question 8

Hot flashes

Answer 8

Bicalutamide

Leuprolide

Question 9

Causes CHF

Answer 9

Trastuzumab

Doxorubicin (chronic use)

Question 10

Pregnancy category D

Answer 10

Trastuzumab

Question 11

Hep B reactivation

Answer 11

Rituximab

Question 12

Bone pain

Answer 12

Filgrastim

Pegfilgrastim

Question 13

Stabilized by leukovorin

Answer 13

5-FU

Question 14

What is capecitabine

Answer 14

Prodrug of 5FU

Question 15

Used in cancers that have up regulated folate receptors

Answer 15

Methotrexate

Question 16

Cytarabine inactivated by

Answer 16

Cytidine deaminase

Question 17

Vesicant (produces blisters)

Answer 17

Doxorubicin

Vincristine

Question 18

Total body alopecia

Answer 18

Paclitaxel

Docetaxel

Question 19

Can cause thromboembolism

Answer 19

Tamoxifen

Question 20

Vaginal dryness / bleeding

Answer 20

Anastrozole

Question 21

Osteoporosis

Answer 21

Anastrozole

Question 22

Osteopenia

Answer 22

Leuprolide

Question 23

Taste issues

Answer 23

Leuprolide

Question 24

Can cause impotence

Answer 24

Leuprolide

Question 25

Proteinuria

Answer 25

Bevaclizumab

Question 26

Biliary excretion

Answer 26

Doxorubicin Irinotecan Vincristine

Question 27

Topo I inhibitor

Answer 27

Irinotecan

Question 28

Magnesium wasting

Answer 28

Cisplatin

Question 29

Reduced GFR

Answer 29

Cisplatin

Question 30

Increased LFTs

Answer 30

Carboplatin

Question 31

Renal problems

Answer 31

``` Cyclophosphamide Ifosfamide Cisplatin Carboplatin Methotrexate (obstruction) ```

Question 32

Conjunctivitis

Answer 32

Cytarabine

Question 33

Pneumonitis

Answer 33

Methotrexate | Cetuximab

Question 34

Diarrhea

Answer 34

``` Irinotecan Imatinib Erlotinib Cetuximab Trastuzumab Ipilimumab Pembrolizumab ```

Question 35

SIADH

Answer 35

Cyclophosphamide Ifosfamide Vincristine

Question 36

Pulmonary issues

Answer 36

Erlotinib

Question 37

Muscle cramps

Answer 37

Imatinib

Question 38

Fluid retention

Answer 38

Docetaxel | Imatinib

Question 39

Fatigue

Answer 39

Erlotinib

Question 40

Bleeding

Answer 40

Sunitinib | Bevaclizumab

Question 41

Flare reaction

Answer 41

Tamoxifen

Question 42

Ocular problems

Answer 42

Tamoxifen

Question 43

Endometrial / uterine cancer

Answer 43

Tamoxifen

Question 44

GI effects

Answer 44

Anastrozole | Leuprolide

Question 45

Amenorrhea

Answer 45

Leuprolide

Question 46

Liver

Answer 46

Carboplatin (incr LFTs) Methotrexate (chronic use) Bicalutamide

Question 47

GI perf

Answer 47

Bevaclizumab

Question 48

Hypertension

Answer 48

Sunitinib Bevaclizumab Erythropoietin

Question 49

Thrombocytopenia

Answer 49

Rituximab

Question 50

Acute death

Answer 50

Rituximab

Question 51

Thrombosis

Answer 51

Tamoxifen | Erythropoietin

Question 52

Seizures

Answer 52

Erythropoietin

Question 53

Hyperuricemia

Answer 53

Filgrastim | Pegfilgrastim