Histo Urinary

Question 0

Blood supply

Answer 0

Renal artery
Interlobar artery
Arcuate artery
Interlobular artery
Afferent arteriole
Glomerular capillaries
Efferent arteriole
Peritubular capillary and vasa recta

Question 1

Renal corpuscle consists of

Answer 1

Bowman’s capsule

Glomerulus

Question 2

Where are there no anastomoses

Answer 2

Interlobular arteries

Question 3

The parietal layer of bowman’s capsule has what epithelium?

Answer 3

Simple squamous

Question 4

What transmembrane proteins are in the diaphragm between pedicels?

Answer 4

Nephrin

Podocin

Question 5

Podocytes are in what layer of Bowman’s capsule?

Answer 5

Visceral layer

Question 6

Where is the blood urine barrier

Answer 6

Between urinary space and visceral layer

Question 7

What is coated with negative charged glycoproteins to repel large anionic proteins?

Answer 7

Glomerular capillary endothelial cells

Question 8

What is the glomerular capillary permeable to?

Answer 8

Water
Urea
Glucose
Small proteins

Question 9

What makes up the glomerular basement membrane?

Answer 9

Fused basal lamina of capillary and visceral layer / podocytes of Bowman’s capsule

Question 10

What are the constituents of the glomerular basement membrane

Answer 10

Type 4 collagen
Laminin
Fibronectin
GAGs

Question 11

Alport’s syndrome

Answer 11

Genetic mutation in genes codin for type 4 collagen

Leaky and thick GBM

Maybe blood in urine

Question 12

Goodpasture’s syndrome

Answer 12

Affect kidney and lung

Autoimmune - make Abs against collagen type 4