Histo

Question 0

Describe cilia

Answer 0

9 pairs of microtubules with a pair in center

At bottom is a cartwheel formation

Question 1

Bottom of cilia

Answer 1

Basal body

Question 2

Cilia vs stereocilia vs microvilli

Answer 2

Cilia - have microtubules inside

Stereocilia - longer than microvilli

Microvilli - shorter

Question 3

What stains the Golgi apparatus?

Answer 3

Defano’s stain

Question 4

The basal lamina is made of

Answer 4

Collagen 4
Actin
Laminin

Question 5

Reticular lamina has

Answer 5

Collagen 3

Question 6

Basal lamina is made by

Answer 6

Epithelial cells

Question 7

Reticular lamina is made by

Answer 7

Connective tissue underneath

Question 8

Functions of cell adhesion molecules

Answer 8

Adhesion
Recognition
Attachment

Question 9

What are the 2 types of cell adhesion molecules and what belongs in each group?

Answer 9

Calcium dependent

• cadherin
• selectin

Calcium independent

• Ig superfamily
• integrin

Question 10

The basement membrane is made up of what 2 layers?

Answer 10

Basal lamina

Reticular lamina

Question 11

What is an important function of the basement membrane

Answer 11

Structural barrier to prevent invasion of tumor cells

Question 12

What is responsible for extravasation of WBCs and homing?

Answer 12

Selectins

Question 13

What is responsible for the T cell receptor (CD4)?

Answer 13

Ig superfamily

Question 14

What is responsible for transendothelial migration?

Answer 14

Ig superfamily

Question 15

Which CAM does cell/cell and cell/matrix interactions?

Answer 15

Integrins

Question 16

What are the 2 main types of junctions?

Answer 16

Occluding (tight) junctions (zonula
occludens)

Anchoring (attachment) junctions

Question 17

Which CAM is in almost all cells?

Answer 17

Integrins

Question 18

What are the 3 ways to describe anchoring junctions

Answer 18

Macula (focal)
Fascia (sheet like)
Zonular (wrap around whole cell)

Question 19

What type of junction regulates diffusion of molecules between adjacent cells?

Answer 19

Tight / occluding junctions

Question 20

What junction is usually between cells with secretory or absorptive functions?

Answer 20

Tight / occluding junctions

Question 21

What 3 organisms destroy occluding / tight junctions?

Answer 21

Clostridium perfringens
H pylori
Dust mites

Question 22

3 types of anchoring / attachment junctions

Answer 22

Zonula adherins (terminal bar)
Desmosome (macula adherins)
Hemidesmosome

Question 23

The zonula adherens can be seen in LM in the apex of columnar cells in the intestine as …

Answer 23

Terminal bar

Question 24

Arrangement of anchoring junctions

Answer 24

``` Intracellular actin Intracellular link protein Extra cellular transmembrane linkers Intracellular link proteins Intracellular actin ```

Question 25

What type of anchoring junction provides mechanical stability in epithelium exposed to tensile and shearing forces?

Answer 25

Desmosome

Question 26

What attaches cells to basal lamina?

Answer 26

Hemidesmosome

Question 27

What are the pore like channels in gap junctions called?

Answer 27

Connexins

Question 28

Where do you find gap junctions?

Answer 28

Embryonic tissues | Adult: cardiac and smooth muscles

Question 29

Microvilli have a core of what filaments?

Answer 29

Actin filaments

Question 30

Function of microvilli

Answer 30

Increase SA for absorption

Question 31

What is a lateral specialization of the cell membrane?

Answer 31

Intercellular interdigitations

Question 32

All epithelial cells rest on

Answer 32

Basal lamina

Question 33

Squamous cells are in (tissue)

Answer 33

Lining blood vessels Air interface in lung Kidney loop of Henle Visceral covering of organs

Question 34

Cuboidal is found in what tissues

Answer 34

Ducts | Kidney tubules

Question 35

Columnar epithelium is found in

Answer 35

GI tract | Female reproductive tract

Question 36

Pseudo stratified columnar epithelium is found in what tissues

Answer 36

Respiratory tract | Male reproductive tract

Question 37

Stratified squamous nonkeratinized is found in what tissues

Answer 37

Esophagus Oral cavity Vagina

Question 38

Specialization of basal cell membrane

Answer 38

Basal infoldings (for ion pumping cells)