Pugacheva Flashcards
(10 cards)
0
Q
Aphidicolin
A
Stops initiation and elongation
*Inhibits DNA Pol alpha (I), delta (III), and epsilon
1
Q
Alpha amanitin
A
Stops initiation and elongation
* inhibits RNA Pol II and III
2
Q
Capecitabine
A
Stops elongation
3
Q
AZT
A
Stops elongation
* is a “bad” nt
4
Q
Cisplatin
A
Prevents forming replication fork
* DNA intercalating that binds G
5
Q
Camptothecin
A
Class I (inhibitor) * inhibits topo I
6
Q
Cloxorubicin
A
Class I (inhibitor) * inhibits topo II
7
Q
Novobiocin
A
Class I (inhibitor) * inhibits gyrase
8
Q
Etoposide
A
Class II (poison) * inhibits topo II
9
Q
Cipro
A
Class II (poison) * inhibits topo II
