Bac Protein Synthesis Inhibitors

Question 0

Aminoglycoside drugs

Answer 0

Gentamicin
Tobramycin
Amikacin

Question 1

Major classes of protein synth inhibitors

Answer 1

Aminoglycosides
Tetracyclines
Macrolides
Lincosamides
Chloramphenicol

Question 2

Tetracycline drugs

Answer 2

Doxycycline

Tigecycline

Question 3

Macrolide drugs

Answer 3

Azithromycin
Clarithromycin
Erythromycin

Question 4

Lincosamide drug

Answer 4

Clindamycin

Question 5

Gentamicin is a type of

Answer 5

Aminoglycoside

Question 6

Tobramycin is a type of

Answer 6

Aminoglycoside

Question 7

Amikacin is a type of

Answer 7

Aminoglycoside

Question 8

Doxycycline is a type of

Answer 8

Tetracycline

Question 9

Tigecycline is a type of

Answer 9

Tetracycline

Question 10

Azithromycin is a type of

Answer 10

Macrolide

Question 11

Clarithromycin is a type of

Answer 11

Macrolide

Question 12

Erythromycin is a type of

Answer 12

Macrolides

Question 13

Clindamycin is a type of

Answer 13

Lincosamide

Question 14

What binds 30S

Answer 14

Aminoglycosides

Tetracyclines

Question 15

What binds 50S

Answer 15

Macrolides
Lincosamides
Chloramphenicol

Question 16

Prevent aatRNA translocation

Answer 16

Macrolides

Lincosamides

Question 17

Prevent transpeptidation

Answer 17

Chloramphenicol

Question 18

Only class of bactericidal protein synth inhibitors

Answer 18

Aminoglycoside

Question 19

Use for aerobic gram negative bac

Answer 19

Aminoglycosides

Question 20

Used for rickettsia

Answer 20

Tetracyclines

Question 21

Used for chlamydia

Answer 21

Tetracyclines

Macrolides

Question 22

Used for mycoplasma pneumoniae

Answer 22

Tetracyclines

Macrolides

Question 23

Used for borrelia burgdorferi

Answer 23

Tetracyclines

Question 24

Used for gram positive cocci

Answer 24

Macrolides | Lincosamides

Question 25

Use for anaerobes above the diaphragm

Answer 25

Lincosamides

Question 26

Used for meningitis

Answer 26

Chloramphenicol

Question 27

What are the meningitis bacteria

Answer 27

N meningitidis H influenzae S pneumoniae

Question 28

Used for acne

Answer 28

Tetracyclines

Question 29

Given IV

Answer 29

Aminoglycosides

Question 30

Distributes to CN 8

Answer 30

Aminoglycosides

Question 31

Excreted via kidney

Answer 31

Aminoglycosides

Question 32

Low TI

Answer 32

Aminoglycosides

Question 33

Milk, antacids, iron, alkaline pH interferes with

Answer 33

Tetracycline

Question 34

Wide distribution except brain and CSF

Answer 34

Macrolides

Question 35

Administered as a prodrug

Answer 35

Chloramphenicol

Question 36

Does distribute to CSF

Answer 36

Chloramphenicol

Question 37

Chloramphenicol inhibits which CYP enzymes

Answer 37

2C19 | 3A4

Question 38

How is chloramphenicol inactivated

Answer 38

Glucuronidation in liver

Question 39

Causes teeth problems in infants

Answer 39

Tetracycline

Question 40

Resistance to Aminoglycosides

Answer 40

Enzymes +P, +NH3, etc to inhibit AG binding to 30S

Question 41

Tetracycline resistance

Answer 41

Protein made to protect 30S from being bound

Question 42

Macrolide resistance

Answer 42

Methylate 23S rRNA (erm gene)

Question 43

Lincosamide resistance

Answer 43

Methylate 23S rRNA (erm gene)

Question 44

Chloramphenicol resistance

Answer 44

Inactivated via acetylation by acetyltransferase

Question 45

Cause ototoxicity

Answer 45

Aminoglycosides

Question 46

Cause nephrotoxicity

Answer 46

Aminoglycosides

Question 47

Causes neuromuscular blockade

Answer 47

Aminoglycosides

Question 48

Causes photosensitization / rash

Answer 48

Tetracyclines

Question 49

Cause teeth discoloration

Answer 49

Tetracyclines

Question 50

Category D / teratogen

Answer 50

Tetracyclines

Question 51

GI distress

Answer 51

Tetracyclines Macrolides Lincosamides

Question 52

Can cause pseudo membranous colitis

Answer 52

Macrolides | Lincosamides

Question 53

Causes arrhythmias

Answer 53

Macrolides

Question 54

Erythromycin with what drug causes sudden cardiac arrest

Answer 54

Verapamil

Question 55

Causes gray baby syndrome

Answer 55

Chloramphenicol

Question 56

Causes anemia

Answer 56

Chloramphenicol