6.17 joints Flashcards
(50 cards)
Chondrocytes injury, proliferation, and death
Osteoarthritis
Degeneration of cartilage
Osteoarthritis
Fissures or fibrillations in joint spaces
Osteoarthritis
Eburnated (smooth) surface
Osteoarthritis
Subchondral synovial cysts
Osteoarthritis
Osteophytes (bony outgrowths)
Osteoarthritis
How to treat osteoarthritis
Symptomatic
Joint replacement
Herbeden nodes
Osteoarthritis
Edema, hyperplasia, and inflammation of synovium
Rheumatoid arthritis
Pannus
Synovium and fibrous tissue that erodes articular cartilage in Rheumatoid arthritis
Ulnar drift
Rheumatoid arthritis
Ankylosis means
Tissue growth that obliterates joint space
Subcutaneous nodules
Rheumatoid arthritis
Central Fibrinous necrotic zone rimmed with epithelioid histiocytes
Rheumatoid nodules in Rheumatoid arthritis
Vasculitis may occur in
Rheumatoid arthritis
Produce self antigens that are citrullinated peptides
Rheumatoid arthritis
Anti-CCP
Rheumatoid arthritis
Treatments of rheumatoid arthritis
Corticosteroids
Methotrexate
TNF antagonists
All relieve pain and inflammation, but only TNF antagonists delay joint destruction
Patients on TNF antagonists for Rheumatoid arthritis are susceptible to
TB
Forms of arthritis before 16 years old that persist for at least 6 weeks
Juvenile idiopathic arthritis
ANA commonly positive
Juvenile idiopathic arthritis
Genetic predisposition
Rheumatoid arthritis
Seronegative spondyloarthropathies
Esthesopathy means
Disorder of bone attachments (ligaments and tendons)
Spondylitis means
Inflammation of vertebrae