6.17 joints Flashcards

(50 cards)

0
Q

Chondrocytes injury, proliferation, and death

A

Osteoarthritis

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1
Q

Degeneration of cartilage

A

Osteoarthritis

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2
Q

Fissures or fibrillations in joint spaces

A

Osteoarthritis

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3
Q

Eburnated (smooth) surface

A

Osteoarthritis

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4
Q

Subchondral synovial cysts

A

Osteoarthritis

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5
Q

Osteophytes (bony outgrowths)

A

Osteoarthritis

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6
Q

How to treat osteoarthritis

A

Symptomatic

Joint replacement

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7
Q

Herbeden nodes

A

Osteoarthritis

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8
Q

Edema, hyperplasia, and inflammation of synovium

A

Rheumatoid arthritis

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9
Q

Pannus

A

Synovium and fibrous tissue that erodes articular cartilage in Rheumatoid arthritis

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10
Q

Ulnar drift

A

Rheumatoid arthritis

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11
Q

Ankylosis means

A

Tissue growth that obliterates joint space

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12
Q

Subcutaneous nodules

A

Rheumatoid arthritis

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13
Q

Central Fibrinous necrotic zone rimmed with epithelioid histiocytes

A

Rheumatoid nodules in Rheumatoid arthritis

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14
Q

Vasculitis may occur in

A

Rheumatoid arthritis

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15
Q

Produce self antigens that are citrullinated peptides

A

Rheumatoid arthritis

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16
Q

Anti-CCP

A

Rheumatoid arthritis

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17
Q

Treatments of rheumatoid arthritis

A

Corticosteroids
Methotrexate
TNF antagonists

All relieve pain and inflammation, but only TNF antagonists delay joint destruction

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18
Q

Patients on TNF antagonists for Rheumatoid arthritis are susceptible to

A

TB

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19
Q

Forms of arthritis before 16 years old that persist for at least 6 weeks

A

Juvenile idiopathic arthritis

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20
Q

ANA commonly positive

A

Juvenile idiopathic arthritis

21
Q

Genetic predisposition

A

Rheumatoid arthritis

Seronegative spondyloarthropathies

22
Q

Esthesopathy means

A

Disorder of bone attachments (ligaments and tendons)

23
Q

Spondylitis means

A

Inflammation of vertebrae

24
Inflammation of SI joint and vertebral processes resulting in spinal ankylosis and immobility
Ankylosing spondylitis
25
Triad in reactive arthritis / Reiter syndrome
Arthritis Urethritis/cervitis Conjunctivitis
26
Triggered by GI or GU infection
Reactive arthritis
27
Arthritis after GI infection
Enteritis-associated arthritis
28
Psoriatic arthritis is a type of
Seronegative spondyloarthropathy
29
Migratory pain in mainly large joints
Lyme arthritis
30
Viral arthritis most commonly caused by
Parvovirus B19
31
Gout involves what crystals
Monosodium urate crystals
32
Pseudogout involves what crystals
Calcium pyrophosphate crystals
33
Tophi
Gout
34
What medication contributes to gout
Thiazides (decrease uric acid excretion)
35
Chalky white deposits
Gout and pseudogout
36
Purple aggregates on H&E stain
Pseudo gout (caused by crystals)
37
Pseudo gout is also called
Chondrocalcinosis
38
Ganglion most commonly in
Wrist
39
No cellular lining of cyst
Ganglion
40
No communication with joint space
Ganglion
41
Fluid filled cyst within CT near joint capsule or tendon sheath
Ganglion
42
Herniation of synovium through joint capsule into adjacent soft tissue
Synovial cyst
43
Baker cyst is a type of
Synovial cyst
44
Baker cyst occurs in setting of
Rheumatoid arthritis
45
Benign neoplasm that arises in synovial lining of joints and tendon sheaths
Tenosynovial giant cell tumors
46
Over express CSF1
Tenosynovial giant cell tumor
47
Mostly composed of macrophages and Multinucleated giant cells
Tenosynovial giant cell tumor
48
Brown color from hemosiderin
Tenosynovial giant cell tumor - diffuse!
49
Type of Tenosynovial giant cell tumor that can be treated with simple excision
Localized