4.8 pharm adrenoreceptor agonists Flashcards

(48 cards)

0
Q

For just cardiogenic or septic shock

A

Norepinephrine

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1
Q

For severe CHF

A

Dopamine

Dobutamine

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2
Q

For shock

A

Norepinephrine (cardiogenic, septic)

Epinephrine (all)

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3
Q

Cardiac emergencies

A

Isoproterenol

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4
Q

Positive inotropy agent

A

Dopamine

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5
Q

Nasal congestion

A

Phenylephrine
Oxymetalozine
Pseudoephedrine
Phenylpropanolamine (off market)

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6
Q

Antihypertensive

A

Clonidine

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7
Q

Asthma

A

Albuterol

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8
Q

Uterine relaxant in premature labor

A

Ritodrine

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9
Q

Treats over active bladder by relaxing detrussor muscle

A

Mirabegron

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10
Q

Postural hypotension

A

Ephedrine

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11
Q

Epinephrine receptor

A

α1, α2, β1, β2

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12
Q

Norepinephrine receptors

A

α1, α2, β1

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13
Q

Isoproterenol receptors

A

β1, β2

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14
Q

Albuterol receptors

A

β2

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15
Q

Dobutamine receptors

A

β1 (some α1, β2)

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16
Q

Phenylephrine receptors

A

α1

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17
Q

Clonidine receptor

A

α2

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18
Q

Alpha methyl NE

A

α2

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19
Q

Mirabegron receptor

20
Q

Indirect acting sympathomimetics

A

Ephedrine
Pseudoephedrine
Amphetamine
Phenylpropanolamine (off market)

21
Q

Use of indirect acting sympathomimetics

A

Alerting
Narcolepsy
Appetite suppression
ADHD

22
Q

Can cause stroke, MI, sudden death

23
Q

Increases in hemorrhagic stroke

A

Phenylpropanolamine

24
Cardiac receptor
β1
25
Smooth muscle contractile adrenoreceptor
α1
26
Smooth muscle relaxant adrenoreceptor
β2
27
Prejunctional adrenoreceptor effects
α2
28
Skin receptors
α1, α2
29
Visceral receptors
α1, α2, some β2
30
Skeletal receptors
α1, α2, β2
31
Low dose vs high dose epi in skeletal muscle
Low dose vasodilation | High dose vasoconstriction
32
Vasoconstriction
α1, some α2
33
Vasodilation
β2
34
Pupillary dilation
α1
35
Airway smooth muscle relaxation
β2
36
Renin release
β1
37
Renin inhibition
α2
38
Nerve inhibit transmitter release
α2
39
β1 on heart has what effects
Incr contractility, HR, arrhythmias, CV
40
What have heteroreceptor effects
Dopamine | Isoproterenol
41
Dopamine receptors
β1 | D1-5
42
Methoxamine receptor
α1
43
Oxymetazoline receptor
α2
44
Ritodrine receptor
β2
45
Metabolized by COMT and MAO
Epinephrine Norepinephrine Dopamine
46
Metabolized by COMT only
Isoproterenol | Dobutamine
47
Metabolized by MAO only
Phenylephrine