Human Function 6 - Goodman Flashcards

(35 cards)

0
Q

Disadvantages of multicellular organisms over unicellular organisms

A

Specialized cells need

1) support (GI, lungs, heart, renal)
2) constant environment / homeostasis

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1
Q

Advantages of multicellular organisms over unicellular organisms

A
  • size
  • complex behaviors
  • adapt
  • sexual reproduction
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2
Q

What messengers do paracrine cells make?

A

Peptides

Small molecules

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3
Q

How do paracrine cells secrete their messengers?

A

Diffusion (if lipophilic)

Exocytosis (if hydrophilic)

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4
Q

Ways to alter transduction of signal from producer to responder

A

1) open/close channels - rapid response
2) increase/decrease enzyme activity - moderately fast
3) induce or repress genes - slow

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5
Q

Time frame of nervous system vs endocrine system

A

NS: rapid
ES: slow

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6
Q

Sites of action for nervous system vs endocrine system

A

NS local

ES diffuse

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7
Q

Specificity of nervous system vs endocrine system

A
NS wiring (neurons)
ES receptors
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8
Q

What parts of the body use both nervous system and endocrine system?

A

Adrenal medulla

Hypothalamus-pituitary

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9
Q

Parts of neuron and their functions

A

Dendrites - input
Cell body - integration
Axon - transmission
Terminal - output

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10
Q

Are neurotransmitters hydrophilic or hydrophobic?

A

Hydrophilic - so they need to be secreted in vesicles because they can’t pass through the membrane

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11
Q

Steps in sending neuronal signals

A

1) action potential
2) depolarization
3) open Ca2+ channels
4) increase levels of Ca2+
5) Exocytosis of neurotransmitter

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12
Q

Types of signal molecules in NS

A

1) classical neurotransmitters (ACh, NE, E)
2) neuropeptides
3) NO

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13
Q

Neuron terminology

A

Based on neurotransmitter

- cholinergic or noradrenergic neurons

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14
Q

Receptor terminology

A

By neurotransmitter and receptor subtype

- cholinergic nicotinic, cholinergic muscarinic, etc

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15
Q

Parts of peripheral nervous system

A

1) sensory system
2) somatic motor system - skeletal muscle
3) autonomic motor system - internal movement

16
Q

Characteristics of somatic motor system

A
  • 1 synapse
  • voluntary
  • excitatory only
  • required for activity
  • all or none response
17
Q

Characteristics of autonomic motor system

A
  • 2 synapses (preganglionic and postganglionic)
  • involuntary
  • excitatory or inhibitory
  • modulate ongoing activity
  • graded response
18
Q

Somatic motor system affects …

A

Skeletal muscle

19
Q

Autonomic motor system affects…

A
  • smooth muscle
  • cardiac muscle
  • glands
20
Q

Divisions of the autonomic nervous system

A

1) enteric (GI)
2) sympathetic
3) parasympathetic

21
Q

Sympathetic: cell bodies in…?

A

Thoracic and lumbar divisions of spinal cord

22
Q

Parasympathetic: cell bodies in…?

A

Brainstem& sacral portion of spinal cord

23
Q

What division of the autonomic NS involves ganglia near the spinal cord?

A

Sympathetic NS

24
What division of the autonomic NS involves ganglia near the organs?
Parasympathetic NS
25
Short pre ganglionic & long post ganglionic in...
Sympathetic NS
26
Long pre ganglionic & short post ganglionic in...
Parasympathetic NS
27
Why does the sympathetic NS act in a diffuse manner?
1) diverse ganglionic innervation (input to many ganglion and post ganglionic axons project to many places) 2) endocrine component (project to adrenal medulla which then releases hormones into bloodstream)
28
What feature in ACh makes it hydrophilic?
Positive charge
29
ACh binds 2 receptors:
Nicotinic | Muscarinic
30
Sympathetic nerves in AUTONOMIC NS release ... (NT)
Norepinephrine
31
Adrenal medulla releases ... (NT)
Epinephrine & norepinephrine
32
Alpha receptors
NE>E | Blood vessels constrict
33
Beta receptors
If E>NE, vasodilation
34
3 pathways a NT can take once released in synapse
1) bind to receptor 2) bind to auto receptor (on pre synaptic axon - always inhibitory) 3) reuptake to be either reutilized or metabolized in mitochondria