6.26 Toxicology

Question 1

The study of the harmful effects of substances on organisms

Answer 1

toxicology

Question 2

cellular / biochemical / molecular mechanisms of toxic effects

Answer 2

mechanistic toxicology

Question 3

toxicity testing, providing info for safety regulation

Answer 3

descriptive toxicology

Question 4

decision-making based on info from mechanistic and descriptive toxicology

Answer 4

regulatory toxicology

Question 5

detecting / identifying harmful substances in body fluids, tissues, etc

Answer 5

forensic toxicology

Question 6

disease caused by toxic substances

Answer 6

clinical toxicology

Question 7

harmful effects on development from prenatal period until puberty

Answer 7

developmental toxicology

Question 8

reproductive effects

Answer 8

reproductive toxicology

Question 9

harmful effects on non-human organisms

Answer 9

environmental toxicology

Question 10

how genetic variants influence toxicity

Answer 10

toxicogenomics

Question 11

something that causes a harmful effect

Answer 11

poison

Question 12

produced by biological systems (plants, animals, bacteria)

Answer 12

toxins

Question 13

produced by human or byproduct of human activities

Answer 13

toxicant

Question 14

a substance not normally found within the body. may be harmful or not

Answer 14

xenobiotic

Question 15

dose at which no biological response occurs

Answer 15

threshold

Question 16

highest dose where not statistically significant

Answer 16

NOAEL (no observed adverse effect level)

Question 17

lowest dose where is statistically significant

Answer 17

LOADL (lowest observed adverse effect level)

Question 18

maximum contaminant levels designated by

Answer 18

EPA

Question 19

permissible exposure limit designated by

Answer 19

OSHA

Question 20

PCB is a type of

Answer 20

organochlorine

Question 21

PCB may cause

Answer 21

chloracne

Question 22

PCBs most found in

Answer 22

electronics

caulk/paint/sealants/finishes

Question 23

drooling, has diarrhea, vomiting, sweating

Answer 23

cholinergics

Question 24

dilated pupils, can’t pee, dry mouth

Answer 24

anticholinergics

Question 25

depressed state, hypo reflexive, decreased vital signs

Answer 25

ethanol or sedative-hypnotic (barb, benzo)

Question 26

hyporeflexive, depressed, pinpoint pupils

Answer 26

opioids

Question 27

tremors, agitated, dilated pupils, increased vital signs

Answer 27

sympathomimetics (or withdrawal from ethanol or sedative hypnotics)

Question 28

tremors, agitated, dilated pupils, increased vital signs, HALLUCINATIONS

Answer 28

withdrawal from ethanol or sedative hypnotics

Question 29

dilated pupils, yawning, vomiting

Answer 29

withdrawal from opioids

Question 30

PCBs bind what receptor

Answer 30

AH (aryl hydrocarbon)

Question 31

PCB metabolism

Answer 31

liver

Question 32

PCB elimination

Answer 32

liver, sebum

Question 33

treatment for PCB

Answer 33

olestra